4EJF
Allosteric peptides that bind to a caspase zymogen and mediate caspase tetramerization
Summary for 4EJF
Entry DOI | 10.2210/pdb4ejf/pdb |
Descriptor | Caspase-6, phage-derived peptide 419, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | caspase-6, zymogen, c163a, caspase, protease, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P55212 |
Total number of polymer chains | 8 |
Total formula weight | 137342.77 |
Authors | Murray, J.M. (deposition date: 2012-04-06, release date: 2012-06-20, Last modification date: 2023-09-13) |
Primary citation | Stanger, K.,Steffek, M.,Zhou, L.,Pozniak, C.D.,Quan, C.,Franke, Y.,Tom, J.,Tam, C.,Elliott, J.M.,Lewcock, J.W.,Zhang, Y.,Murray, J.,Hannoush, R.N. Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization. Nat.Chem.Biol., 8:655-660, 2012 Cited by PubMed: 22683611DOI: 10.1038/nchembio.967 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6465 Å) |
Structure validation
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