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3EDR

The crystal structure of caspase-7 in complex with Acetyl-LDESD-CHO

Summary for 3EDR
Entry DOI10.2210/pdb3edr/pdb
Related3EDQ
Related PRD IDPRD_000241
DescriptorCaspase-7, Inhibitor Ac-ldesd-cho peptide, ... (4 entities in total)
Functional Keywordscaspase, peptide inhibitor, apoptosis, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm: P55210 P55210
Total number of polymer chains6
Total formula weight63014.11
Authors
Agniswamy, J. (deposition date: 2008-09-03, release date: 2008-10-28, Last modification date: 2023-11-15)
Primary citationFu, G.,Chumanevich, A.A.,Agniswamy, J.,Fang, B.,Harrison, R.W.,Weber, I.T.
Structural basis for executioner caspase recognition of P5 position in substrates.
Apoptosis, 13:1291-1302, 2008
Cited by
PubMed: 18780184
DOI: 10.1007/s10495-008-0259-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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