3EDQ
Crystal structure of Caspase-3 with inhibitor AC-LDESD-CHO
Summary for 3EDQ
Entry DOI | 10.2210/pdb3edq/pdb |
Related | 3EDL |
Descriptor | Caspase-3, AC-LDESD-CHO peptide, ... (4 entities in total) |
Functional Keywords | enzyme catalysis, cysteine protease, apoptosis, s-nitrosylation, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P42574 P42574 |
Total number of polymer chains | 6 |
Total formula weight | 59933.93 |
Authors | |
Primary citation | Fu, G.,Chumanevich, A.A.,Agniswamy, J.,Fang, B.,Harrison, R.W.,Weber, I.T. Structural basis for executioner caspase recognition of P5 position in substrates. Apoptosis, 13:1291-1302, 2008 Cited by PubMed: 18780184DOI: 10.1007/s10495-008-0259-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
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