Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR CHAIN E OF AC-LDESD-CHO PEPTIDE |
| Chain | Residue |
| A | MET61 |
| B | TRP206 |
| B | ARG207 |
| B | ASN208 |
| B | SER209 |
| B | TRP214 |
| B | GLU248 |
| B | SER249 |
| B | PHE250 |
| E | HOH143 |
| E | HOH154 |
| A | SER63 |
| E | HOH181 |
| E | HOH252 |
| E | HOH275 |
| A | ARG64 |
| A | HIS121 |
| A | GLY122 |
| A | GLN161 |
| A | CYS163 |
| B | TYR204 |
| B | SER205 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR CHAIN F OF AC-LDESD-CHO PEPTIDE |
| Chain | Residue |
| C | ARG64 |
| C | HIS121 |
| C | GLY122 |
| C | GLN161 |
| C | CYS163 |
| D | TYR204 |
| D | SER205 |
| D | TRP206 |
| D | ARG207 |
| D | ASN208 |
| D | SER209 |
| D | TRP214 |
| D | SER249 |
| D | PHE250 |
| F | HOH139 |
| F | HOH200 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HskrsSfvCvLLSHG |
| Chain | Residue | Details |
| A | HIS108-GLY122 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKLFIIQACRG |
| Chain | Residue | Details |
| A | LYS154-GLY165 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ARG207 | |
| D | ARG207 | |
| C | HIS121 | |
| C | CYS163 | |
| Chain | Residue | Details |
| A | CYS163 | |
| C | CYS163 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| A | HIS121 | |
| A | GLY122 | |
| A | CYS163 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| C | HIS121 | |
| C | GLY122 | |
| C | CYS163 | |
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 815 |
| Chain | Residue | Details |
| A | THR62 | electrostatic stabiliser |
| A | SER63 | electrostatic stabiliser |
| A | HIS121 | electrostatic stabiliser, proton acceptor, proton donor |
| A | GLY122 | electrostatic stabiliser |
| A | CYS163 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 815 |
| Chain | Residue | Details |
| C | THR62 | electrostatic stabiliser |
| C | SER63 | electrostatic stabiliser |
| C | HIS121 | electrostatic stabiliser, proton acceptor, proton donor |
| C | GLY122 | electrostatic stabiliser |
| C | CYS163 | electrostatic stabiliser |
