4DCO
Crystal Structure of caspase 3, L168Y mutant
Summary for 4DCO
Entry DOI | 10.2210/pdb4dco/pdb |
Related | 4DCJ 4DCP |
Related PRD ID | PRD_000422 |
Descriptor | Caspase-3 subunit p17, Caspase-3 subunit p12, Caspase Inhibitor AC-DEVD-CHO, ... (4 entities in total) |
Functional Keywords | alpha/beta hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P42574 P42574 |
Total number of polymer chains | 6 |
Total formula weight | 59835.78 |
Authors | |
Primary citation | Kang, H.J.,Lee, Y.M.,Jeong, M.S.,Kim, M.,Bae, K.H.,Kim, S.J.,Chung, S.J. Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32:305-313, 2012 Cited by PubMed: 22304005DOI: 10.1042/BSR20120009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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