PDB: 161 resultsInfo pagesStatus searchChemie searchBIRD

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8T09	Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-ethynyl-2-hydroxy-1-naphthaldehyde) Descriptor: 6-ethynyl-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Bruystens, J.G.H. Deposit date: 2023-05-31 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors. Acs Pharmacol Transl Sci, 6, 2023
6OQ4	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1 Descriptor: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.754 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
6OQ3	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2 Descriptor: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
2YS3	Solution structure of the PH domain of Kindlin-3 from human Descriptor: Unc-112-related protein 2 Authors: Li, H, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-04-03 Release date: 2007-10-09 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the PH domain of Kindlin-3 from human To be Published
5D68	Crystal structure of KRIT1 ARD-FERM Descriptor: Krev interaction trapped protein 1 Authors: Zhang, R, Li, X, Boggon, T.J. Deposit date: 2015-08-11 Release date: 2015-10-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.908 Å) Cite: Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface. J.Struct.Biol., 192, 2015
4BBK	Structural and functional characterisation of the kindlin-1 pleckstrin homology domain Descriptor: FERMITIN FAMILY HOMOLOG 1, GLYCEROL Authors: Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. Deposit date: 2012-09-25 Release date: 2012-11-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
4DXA	Co-crystal structure of Rap1 in complex with KRIT1 Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Li, X, Zhang, R, Boggon, T.J. Deposit date: 2012-02-27 Release date: 2012-05-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1). J.Biol.Chem., 287, 2012
4F7H	The crystal structure of kindlin-2 pleckstrin homology domain in free form Descriptor: Fermitin family homolog 2, S,R MESO-TARTARIC ACID Authors: Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. Deposit date: 2012-05-16 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
2LKO	Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation Descriptor: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE Authors: Liu, J, Fukuda, K, Xu, Z. Deposit date: 2011-10-17 Release date: 2011-10-26 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J.Biol.Chem., 286, 2011
6T36	Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide Descriptor: BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 Authors: Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. Deposit date: 2019-10-10 Release date: 2021-01-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
6UZK	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi6 Descriptor: 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-11-15 Release date: 2020-11-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.924 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells. Faseb Bioadv, 3, 2021

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