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4AQR
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BU of 4aqr by Molmil
Crystal structure of calmodulin in complex with the regulatory domain of a plasma-membrane Ca2+-ATPase
Descriptor: CALCIUM ION, CALCIUM-TRANSPORTING ATPASE 8, PLASMA MEMBRANE-TYPE, ...
Authors:Tidow, H, Poulsen, L.R, Andreeva, A, Hein, K.L, Palmgren, M.G, Nissen, P.
Deposit date:2012-04-19
Release date:2012-10-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Bimodular Mechanism of Calcium Control in Eukaryotes
Nature, 491, 2012
4YYK
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BU of 4yyk by Molmil
Crystal structure of BRD9 Bromodomain bound to a crotonyllysine peptide
Descriptor: Bromodomain-containing protein 9, Histone H4
Authors:Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
Deposit date:2015-03-24
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
6I7E
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BU of 6i7e by Molmil
Plasmodium falciparum Myosin A, Pre-powerstroke
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-A, ...
Authors:Robert-Paganin, J, Auguin, D, Moussaoui, D, Jousset, G, Baum, J, Trybus, K.M, Houdusse, A.
Deposit date:2018-11-16
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.492 Å)
Cite:Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism.
Nat Commun, 10, 2019
5X5I
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BU of 5x5i by Molmil
The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli
Descriptor: HTH-type transcriptional regulator RcdA
Authors:Sugino, H, Usui, M, Shimada, T, Nakano, M, Ogasawara, H, Ishihama, A, Hirata, A.
Deposit date:2017-02-16
Release date:2017-12-27
Method:X-RAY DIFFRACTION (2.554 Å)
Cite:A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation.
FEBS Lett., 591, 2017
3KMZ
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BU of 3kmz by Molmil
Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment
Descriptor: 4-{(E)-2-[5,5-dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoic acid, GLYCEROL, Nuclear receptor corepressor 1, ...
Authors:Bourguet, W, le Maire, A.
Deposit date:2009-11-11
Release date:2010-06-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor.
Nat.Struct.Mol.Biol., 17, 2010
5W9H
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BU of 5w9h by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3HP8
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BU of 3hp8 by Molmil
Crystal structure of a designed Cyanovirin-N homolog lectin; LKAMG, bound to sucrose
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cyanovirin-N-like protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Koharudin, L.M.I, Furey, W, Gronenborn, A.M.
Deposit date:2009-06-03
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose binding.
Proteins, 77, 2009
2WPX
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BU of 2wpx by Molmil
Tandem GNAT protein from the clavulanic acid biosynthesis pathway (with AcCoA)
Descriptor: ACETYL COENZYME *A, GLYCEROL, ORF14
Authors:Iqbal, A, Arunlanantham, H, McDonough, M.A, Chowdhury, R, Clifton, I.J.
Deposit date:2009-08-11
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.
Proteins, 78, 2010
5ES1
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BU of 5es1 by Molmil
CRYSTAL STRUCTURE OF MICROTUBULE AFFINITY-REGULATING KINASE 4 CATALYTIC DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR
Descriptor: MAP/microtubule affinity-regulating kinase 4, ~{N}-[(1~{R},6~{R})-6-azanyl-2,2-bis(fluoranyl)cyclohexyl]-5-ethyl-4-[6-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide
Authors:Sack, J.S.
Deposit date:2015-11-16
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor.
Acta Crystallogr F Struct Biol Commun, 72, 2016
2WV4
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BU of 2wv4 by Molmil
Crystal structure of foot-and-mouth disease virus 3C protease in complex with a decameric peptide corresponding to the VP1-2A cleavage junction
Descriptor: FOOT AND MOUTH DISEASE VIRUS (SEROTYPE A) VARIANT VP1 CAPSID PROTEIN, PICORNAIN 3C
Authors:Zunszain, P.A, Knox, S.R, Sweeney, T.R, Yang, J, Roque-Rosell, N, Belsham, G.J, Leatherbarrow, R.J, Curry, S.
Deposit date:2009-10-13
Release date:2009-10-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights Into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate.
J.Mol.Biol., 395, 2010
5G51
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BU of 5g51 by Molmil
High resolution structure of the part of VP3 protein of Deformed Wing Virus forming P-domain
Descriptor: DWV-VP3-P-DOMAIN
Authors:Skubnik, K, Novacek, J, Fuzik, T, Pridal, A, Paxton, R, Plevka, P.
Deposit date:2016-05-18
Release date:2017-03-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of deformed wing virus, a major honey bee pathogen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ZUZ
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BU of 6zuz by Molmil
TFIIS N-terminal domain (TND) from human Elongin-A
Descriptor: Elongin-A
Authors:Veverka, V.
Deposit date:2020-07-23
Release date:2021-12-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
5W9I
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BU of 5w9i by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4YYH
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BU of 4yyh by Molmil
Crystal structure of BRD9 Bromodomain bound to a crotonyllysine peptide
Descriptor: Bromodomain-containing protein 9, Histone H4
Authors:Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
Deposit date:2015-03-23
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYN
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BU of 4yyn by Molmil
Crystal structure of TAF1 BD2 Bromodomain bound to a crotonyllysine peptide
Descriptor: Histone H4, Transcription initiation factor TFIID subunit 1
Authors:Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
Deposit date:2015-03-24
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
5W9L
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BU of 5w9l by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6BZY
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BU of 6bzy by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the 22D11 broadly neutralizing antibody
Descriptor: 22D11 Heavy Chain, 22D11 Light Chain, E2 AS412 peptide
Authors:Tzarum, N, Aleman, F, Wilson, I.A, Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4YYM
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BU of 4yym by Molmil
Crystal structure of TAF1 BD2 Bromodomain bound to a butyryllysine peptide
Descriptor: CALCIUM ION, Histone H4, Transcription initiation factor TFIID subunit 1
Authors:Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
Deposit date:2015-03-24
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
5ZX5
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BU of 5zx5 by Molmil
3.3 angstrom structure of mouse TRPM7 with EDTA
Descriptor: CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7
Authors:Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E.
Deposit date:2018-05-18
Release date:2018-10-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W9K
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BU of 5w9k by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4YYJ
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BU of 4yyj by Molmil
Crystal structure of BRD9 Bromodomain bound to a butyryllysine peptide
Descriptor: Bromodomain-containing protein 9, Histone H4
Authors:Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
Deposit date:2015-03-23
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
1Q78
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BU of 1q78 by Molmil
Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Poly(A) polymerase alpha
Authors:Martin, G, Moglich, A, Keller, W, Doublie, S.
Deposit date:2003-08-16
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase.
J.Mol.Biol., 341, 2004
5V7I
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BU of 5v7i by Molmil
Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Descriptor: (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D.
Deposit date:2017-03-20
Release date:2017-10-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3HOP
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BU of 3hop by Molmil
Structure of the actin-binding domain of human filamin A
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-03
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
1QFU
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BU of 1qfu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ...
Authors:Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M.
Deposit date:1999-04-14
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999

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