8DZL
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![BU of 8dzl by Molmil](/molmil-images/mine/8dzl) | Structure of the K39Q mutant of rat somatic Cytochrome c at 1.36A | Descriptor: | Cytochrome c, somatic, HEME C | Authors: | Edwards, B.F.P, Huettemann, M, Vaishnav, A, Brunzelle, J, Morse, P, Wan, J. | Deposit date: | 2022-08-08 | Release date: | 2023-07-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle. Nat Commun, 14, 2023
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8E67
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8E66
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![BU of 8e66 by Molmil](/molmil-images/mine/8e66) | ETV6 H396Y variant bound to DNA containing the sequence GGAA | Descriptor: | CACODYLATE ION, Complementary 15 bp strand, GGAA-containing 15 bp DNA, ... | Authors: | Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P. | Deposit date: | 2022-08-22 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The functional role of histidine within the ETV6 ETS domain to be published
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8ECZ
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![BU of 8ecz by Molmil](/molmil-images/mine/8ecz) | Bovine Fab 4C1 | Descriptor: | 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-09-02 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EDF
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8ECQ
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![BU of 8ecq by Molmil](/molmil-images/mine/8ecq) | Bovine Fab 2G3 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-09-02 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ECV
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![BU of 8ecv by Molmil](/molmil-images/mine/8ecv) | Bovine Fab 2F12 | Descriptor: | 2F12 Fab Heavy chain, 2F12 Fab Light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-09-02 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ED1
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![BU of 8ed1 by Molmil](/molmil-images/mine/8ed1) | Bovine Fab 5C1 | Descriptor: | 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-09-02 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EGD
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![BU of 8egd by Molmil](/molmil-images/mine/8egd) | Branched chain ketoacid dehydrogenase kinase in complex with inhibitor | Descriptor: | 5-(4-methoxyphenyl)-1H-tetrazole, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Liu, S. | Deposit date: | 2022-09-12 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors. J.Biol.Chem., 299, 2023
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8EGQ
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![BU of 8egq by Molmil](/molmil-images/mine/8egq) | Branched chain ketoacid dehydrogenase kinase complexes | Descriptor: | (2S)-2-ethyl-4-{[(2'M)-2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... | Authors: | Liu, S. | Deposit date: | 2022-09-13 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.955 Å) | Cite: | Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors. J.Biol.Chem., 299, 2023
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8EGF
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![BU of 8egf by Molmil](/molmil-images/mine/8egf) | Branched chain ketoacid dehydrogenase kinase in complex with inhibitor | Descriptor: | (5P)-5-(4'-methyl[1,1'-biphenyl]-2-yl)-1H-tetrazole, ADENOSINE-5'-DIPHOSPHATE, POTASSIUM ION, ... | Authors: | Liu, S. | Deposit date: | 2022-09-12 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors. J.Biol.Chem., 299, 2023
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8EGU
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![BU of 8egu by Molmil](/molmil-images/mine/8egu) | Branched chain ketoacid dehydrogenase kinase complexes | Descriptor: | (2~{S})-3-methyl-2-[pentanoyl-[[4-[2-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... | Authors: | Liu, S. | Deposit date: | 2022-09-13 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.923 Å) | Cite: | Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors. J.Biol.Chem., 299, 2023
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8DDG
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8DDH
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8DDF
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![BU of 8ddf by Molmil](/molmil-images/mine/8ddf) | Quasi-racemic mixture of L-FWF and D-FYF peptide reveals rippled beta-sheet | Descriptor: | 1,1,1,3,3,3-hexafluoropropan-2-ol, DPN-DTY-DPN, PHE-TRP-PHE | Authors: | Sawaya, M.R, Hazari, A, Eisenberg, D.E. | Deposit date: | 2022-06-18 | Release date: | 2022-09-28 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The rippled beta-sheet layer configuration-a novel supramolecular architecture based on predictions by Pauling and Corey. Chem Sci, 13, 2022
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8EPW
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![BU of 8epw by Molmil](/molmil-images/mine/8epw) | Crystal Structure of KRAS4b-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF | Descriptor: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. | Deposit date: | 2022-10-06 | Release date: | 2023-06-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D . Commun Biol, 6, 2023
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8F43
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![BU of 8f43 by Molmil](/molmil-images/mine/8f43) | HNH Nuclease Domain from G. stearothermophilus Cas9, K597A mutant | Descriptor: | CRISPR-associated endonuclease Cas9 | Authors: | D'Ordine, A.M, Belato, H.B, Lisi, G.P, Jogl, G. | Deposit date: | 2022-11-10 | Release date: | 2022-12-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage. J.Chem.Phys., 157, 2022
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8ELL
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![BU of 8ell by Molmil](/molmil-images/mine/8ell) | Apo human biliverdin reductase beta (cryogenic) | Descriptor: | Flavin reductase (NADPH), SODIUM ION | Authors: | McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E. | Deposit date: | 2022-09-26 | Release date: | 2023-09-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle. Front Mol Biosci, 10, 2023
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8ELM
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![BU of 8elm by Molmil](/molmil-images/mine/8elm) | Apo human biliverdin reductase beta (293K) | Descriptor: | Flavin reductase (NADPH), SODIUM ION | Authors: | McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E. | Deposit date: | 2022-09-26 | Release date: | 2023-09-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle. Front Mol Biosci, 10, 2023
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8F5Q
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![BU of 8f5q by Molmil](/molmil-images/mine/8f5q) | Crystal structure of human PCNA in complex with the PIP box of FBH1 | Descriptor: | F-box DNA helicase 1, Proliferating cell nuclear antigen | Authors: | Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T. | Deposit date: | 2022-11-15 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular insight into the PCNA-binding mode of FBH1. Structure, 31, 2023
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8F1F
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![BU of 8f1f by Molmil](/molmil-images/mine/8f1f) | Structure of K48-linked tri-ubiquitin in complex with cyclic peptide | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Non-proteinogenic cyclic peptide (inhibitor), ... | Authors: | Lubkowski, J, Fushman, D, Lemma, B. | Deposit date: | 2022-11-05 | Release date: | 2023-11-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nat Commun, 14, 2023
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8F5X
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![BU of 8f5x by Molmil](/molmil-images/mine/8f5x) | Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP) | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Non-secretory ribonuclease, ... | Authors: | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2022-11-15 | Release date: | 2023-11-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. J.Biol.Chem., 300, 2024
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8F47
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8F65
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8EZ6
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![BU of 8ez6 by Molmil](/molmil-images/mine/8ez6) | |