8EZ6

The DBC1/SIRT1 Interaction is Choreographed by Post-translational Modification

Summary for 8EZ6

Entry DOI	10.2210/pdb8ez6/pdb
Descriptor	Cell cycle and apoptosis regulator protein 2 (2 entities in total)
Functional Keywords	dbc1, s1-like, insulin signaling, liver metabolism, chaperone, gene regulation
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	16000.15
Authors	Krzysiak, T.C.,Gronenborn, A.M. (deposition date: 2022-10-31, release date: 2024-03-27, Last modification date: 2024-04-17)
Primary citation	Krzysiak, T.C.,Choi, Y.J.,Kim, Y.J.,Yang, Y.,DeHaven, C.,Thompson, L.,Ponticelli, R.,Mermigos, M.M.,Thomas, L.,Marquez, A.,Sipula, I.,Kemper, J.K.,Jurczak, M.,Thomas, G.,Gronenborn, A.M. Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification. Protein Sci., 33:e4938-e4938, 2024 Cited by PubMed: 38533551 DOI: 10.1002/pro.4938 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation