PDB: 215264 resultsInfo pagesStatus searchChemie searchBIRD

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4XYF	Crystal structure of c-Met in complex with (S)-5-(8-fluoro-3-(1-(3-(2-methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-methylisoxazole Descriptor: 6-{(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline, Hepatocyte growth factor receptor Authors: Whittington, D.A, Long, A.M. Deposit date: 2015-02-02 Release date: 2015-03-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors. J.Med.Chem., 58, 2015
8J2E	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
5CID	Complex of yeast cytochrome c peroxidase (W191G) bound to o-toluidine with iso-1 cytochrome c Descriptor: 2-methylaniline, Cytochrome c iso-1, Cytochrome c peroxidase, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-12 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.763 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
8RXF	Crystal structure of S-SAD phased alpha-keto C-methyl transferase SgvM bound to ketoleucine Descriptor: 2-OXO-4-METHYLPENTANOIC ACID, CHLORIDE ION, GLYCEROL, ... Authors: Gerhardt, S, Andexer, J.N. Deposit date: 2024-02-07 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structures and protein engineering of the alpha-keto acid C-methyltransferases SgvM and MrsA for rational substrate transfer. Chembiochem, 2024
8J2B	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2A	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ Descriptor: GLYCEROL, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8RVS	Crystal structure of alpha keto acid C-methyl-transferases MrsA bound to SAM Descriptor: 1,2-ETHANEDIOL, 2-ketoarginine methyltransferase, DI(HYDROXYETHYL)ETHER, ... Authors: Gerhardt, S, Andexer, J.N. Deposit date: 2024-02-02 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.632 Å) Cite: Structures and protein engineering of the alpha-keto acid C-methyltransferases SgvM and MrsA for rational substrate transfer. Chembiochem, 2024
8RWM	Crystal structure of selenomethionine derivatized alpha keto acid C-methyl-transferases MrsA Descriptor: 2-ketoarginine methyltransferase, MAGNESIUM ION, SODIUM ION Authors: Gerhardt, S, Andexer, J.N. Deposit date: 2024-02-05 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.644 Å) Cite: Structures and protein engineering of the alpha-keto acid C-methyltransferases SgvM and MrsA for rational substrate transfer. Chembiochem, 2024
7L0O	Streptococcus gordonii C123 Domain(s)-Structural and Functional Analysis Descriptor: Agglutinin receptor, CALCIUM ION Authors: Schormann, N, Deivanayagam, C. Deposit date: 2020-12-11 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and functional analysis of the C-terminal region of Streptococcus gordonii SspB. Acta Crystallogr D Struct Biol, 77, 2021
7TRW	Crystal Structure of the C-terminal Ligand-Binding Domain of the LysR family Transcriptional Regulator YfbA from Yersinia pestis Descriptor: 3-HYDROXYBENZOIC ACID, LysR-family transcriptional regulatory protein, PHOSPHATE ION Authors: Kim, Y, Tesar, C, Crawford, M, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2022-01-31 Release date: 2022-02-09 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Crystal Structure of the C-terminal Ligand-Binding Domain of the LysR family Transcriptional Regulator YfbA from Yersinia pestis To Be Published
5CIC	Complex of yeast cytochrome c peroxidase (W191G) bound to 3-aminobenzotrifluoride with iso-1 cytochrome c Descriptor: 3-(trifluoromethyl)aniline, Cytochrome c iso-1, Cytochrome c peroxidase, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-11 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.103 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
7BBT	Structure of cytochrome c in complex with a p-benzyl-sulfonato-calix[8]arene-PEG pseudorotaxane Descriptor: 4-[[49,50,51,52,53,54,55,56-octahydroxy-11,17,23,29,35,41,47-heptakis[(4-sulfonatophenyl)methyl]-5-nonacyclo[43.3.1.13,7.19,13.115,19.121,25.127,31.133,37.139,43]hexapentaconta-1(49),3,5,7(56),9,11,13(55),15,17,19(54),21,23,25(53),27,29,31(52),33,35,37(51),39,41,43(50),45,47-tetracosaenyl]methyl]benzenesulfonate, Cytochrome c iso-1, HEME C, ... Authors: Mockler, N.M, Ramberg, K, Guagnini, F, Raston, C.L, Crowley, P.B. Deposit date: 2020-12-18 Release date: 2021-10-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.023 Å) Cite: Noncovalent Protein-Pseudorotaxane Assembly Incorporating an Extended Arm Calix[8]arene with alpha-Helical Recognition Properties. Cryst.Growth Des., 21, 2021
5CIH	Complex of yeast cytochrome c peroxidase (W191Y) with iso-1 cytochrome c Descriptor: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-12 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
8T3J	Crystal structure of native exfoliative toxin C (ExhC) from Mammaliicoccus sciuri Descriptor: Exfoliative toxin C Authors: Calil, F.A, Gismene, C, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. Deposit date: 2023-06-07 Release date: 2023-11-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.705 Å) Cite: Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024
5CIG	Complex of yeast cytochrome c peroxidase (W191G) with iso-1 cytochrome c Descriptor: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-12 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
7BMC	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-01-19 Release date: 2022-03-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
7BM9	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide Descriptor: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-01-19 Release date: 2022-03-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
5CIE	Complex of yeast cytochrome c peroxidase (W191G) bound to aniline with iso-1 cytochrome c Descriptor: ANILINE, Cytochrome c iso-1, Cytochrome c peroxidase, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-12 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
5CIF	Complex of yeast cytochrome c peroxidase (W191F) with iso-1 cytochrome c Descriptor: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ... Authors: Crane, B.R, Payne, T.M. Deposit date: 2015-07-12 Release date: 2016-08-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c. Biochemistry, 55, 2016
5GMJ	Crystal Structure of GRASP55 GRASP domain in complex with JAM-B C-terminus Descriptor: Golgi reassembly-stacking protein 2, Junctional adhesion molecule B Authors: Shi, N, Shi, X, Morelli, X, Betzi, S, Huang, X. Deposit date: 2016-07-14 Release date: 2017-05-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.986 Å) Cite: Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis PLoS Genet., 13, 2017
6TKK	Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide Descriptor: 1,2-ETHANEDIOL, ACE-ARG-PRO-GLN-PRO-ARG, Neuropilin-1 Authors: Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. Deposit date: 2019-11-28 Release date: 2020-12-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.06 Å) Cite: Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide To Be Published
7B3W	Crystal structure of c-MET bound by compound 4 Descriptor: 1,2-ETHANEDIOL, 3-(6-fluoranyl-1~{H}-indazol-4-yl)-4,5-dihydro-1~{H}-pyrrolo[3,4-b]pyrrol-6-one, Hepatocyte growth factor receptor Authors: Collie, G.W. Deposit date: 2020-12-01 Release date: 2020-12-09 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Structural Basis for Targeting the Folded P-Loop Conformation of c-MET. Acs Med.Chem.Lett., 12, 2021
7B43	Crystal structure of c-MET bound by compound 9 Descriptor: 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine, Hepatocyte growth factor receptor Authors: Collie, G.W. Deposit date: 2020-12-02 Release date: 2020-12-09 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural Basis for Targeting the Folded P-Loop Conformation of c-MET. Acs Med.Chem.Lett., 12, 2021
8DNQ	BRD2-BD1 in complex with cyclic peptide 2.2B Descriptor: Bromodomain-containing protein 2, Cyclic peptide 2.2B, GLYCEROL Authors: Patel, K, Franck, C, Mackay, J.P. Deposit date: 2022-07-11 Release date: 2023-07-19 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins. Structure, 31, 2023
6S8O	Human Brr2 Helicase Region M641C/A1582C Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase Authors: Vester, K, Santos, K.F, Wahl, M.C. Deposit date: 2019-07-10 Release date: 2020-01-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.172 Å) Cite: The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020

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