4LOK
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![BU of 4lok by Molmil](/molmil-images/mine/4lok) | Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p] | Descriptor: | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4F5D
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![BU of 4f5d by Molmil](/molmil-images/mine/4f5d) | ERIS/STING in complex with ligand | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Transmembrane protein 173 | Authors: | Huang, Y.H, Liu, X.Y, Su, X.D. | Deposit date: | 2012-05-13 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
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4F9G
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![BU of 4f9g by Molmil](/molmil-images/mine/4f9g) | Crystal structure of STING complex with Cyclic di-GMP. | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Transmembrane protein 173 | Authors: | Kabaleeswaran, V, Wu, H. | Deposit date: | 2012-05-18 | Release date: | 2012-07-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING. Mol.Cell, 46, 2012
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4GIZ
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![BU of 4giz by Molmil](/molmil-images/mine/4giz) | Crystal structure of full-length human papillomavirus oncoprotein E6 in complex with LXXLL peptide of ubiquitin ligase E6AP at 2.55 A resolution | Descriptor: | Maltose-binding periplasmic protein, UBIQUITIN LIGASE EA6P: chimeric protein, Protein E6, ... | Authors: | McEwen, A.G, Zanier, K, Charbonnier, S, Poussin, P, Cura, V, Vande Pol, S, Trave, G, Cavarelli, J. | Deposit date: | 2012-08-09 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins. Science, 339, 2013
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4EMU
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![BU of 4emu by Molmil](/molmil-images/mine/4emu) | Crystal structure of ligand free human STING | Descriptor: | CALCIUM ION, Transmembrane protein 173 | Authors: | Li, P. | Deposit date: | 2012-04-12 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
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4EMT
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![BU of 4emt by Molmil](/molmil-images/mine/4emt) | Crystal Structure of human STING bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | Authors: | Li, P. | Deposit date: | 2012-04-12 | Release date: | 2012-06-13 | Last modified: | 2012-07-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
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4F5Y
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![BU of 4f5y by Molmil](/molmil-images/mine/4f5y) | Crystal structure of human STING CTD complex with C-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | Authors: | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | Deposit date: | 2012-05-13 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP Nat.Struct.Mol.Biol., 19, 2012
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4F5W
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![BU of 4f5w by Molmil](/molmil-images/mine/4f5w) | Crystal structure of ligand free human STING CTD | Descriptor: | CALCIUM ION, Transmembrane protein 173 | Authors: | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | Deposit date: | 2012-05-13 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP Nat.Struct.Mol.Biol., 19, 2012
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4F9E
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![BU of 4f9e by Molmil](/molmil-images/mine/4f9e) | |
4EFO
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![BU of 4efo by Molmil](/molmil-images/mine/4efo) | Crystal structure of the ubiquitin-like domain of human TBK1 | Descriptor: | Serine/threonine-protein kinase TBK1 | Authors: | Li, J, Li, J, Miyahira, A, Sun, J, Liu, Y, Cheng, G, Liang, H. | Deposit date: | 2012-03-30 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.769 Å) | Cite: | Crystal structure of the ubiquitin-like domain of human TBK1. Protein Cell, 3, 2012
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4F5E
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![BU of 4f5e by Molmil](/molmil-images/mine/4f5e) | Crystal structure of ERIS/STING | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Transmembrane protein 173 | Authors: | Huang, Y.H, Liu, X.Y, Su, X.D. | Deposit date: | 2012-05-13 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
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4GHL
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![BU of 4ghl by Molmil](/molmil-images/mine/4ghl) | Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Ramanan, P, Borek, D.M, Otwinowski, Z, Leung, D.W, Amarasinghe, G.K. | Deposit date: | 2012-08-07 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proc.Natl.Acad.Sci.USA, 109, 2012
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