4GHL

Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms

Summary for 4GHL

• Entry DOI: 10.2210/pdb4ghl/pdb
• Related: 3FKE 3L25 3L26 3L27 3L28 3L29
• Descriptor: short palindromic RNA AGACAGCAUAUGCUGUCU, Polymerase cofactor VP35, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: protein-rna complex, vp35, ifn inhibitor, rna binding protein, interferon antagonism, double stranded rna, transcription, viral protein-rna complex, viral protein/rna
• Biological source: Lake Victoria marburgvirus (MARV); More
• Cellular location: Virion: Q03039
• Total number of polymer chains: 6
• Total formula weight: 70679.82

Authors

Ramanan, P.,Borek, D.M.,Otwinowski, Z.,Leung, D.W.,Amarasinghe, G.K. (deposition date: 2012-08-07, release date: 2012-11-28, Last modification date: 2023-09-13)

• Primary citation: Ramanan, P.,Edwards, M.R.,Shabman, R.S.,Leung, D.W.,Endlich-Frazier, A.C.,Borek, D.M.,Otwinowski, Z.,Liu, G.,Huh, J.,Basler, C.F.,Amarasinghe, G.K.; Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.; Proc.Natl.Acad.Sci.USA, 109:20661-20666, 2012; PubMed: 23185024; DOI: 10.1073/pnas.1213559109

Experimental method

X-RAY DIFFRACTION (2.02 Å)