4F5E

Crystal structure of ERIS/STING

Summary for 4F5E

• Entry DOI: 10.2210/pdb4f5e/pdb
• Related: 4F5D
• Descriptor: Transmembrane protein 173, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
• Functional Keywords: receptor, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein: Q86WV6
• Total number of polymer chains: 1
• Total formula weight: 28861.68

Authors

Huang, Y.H.,Liu, X.Y.,Su, X.D. (deposition date: 2012-05-13, release date: 2012-06-27, Last modification date: 2024-03-20)

• Primary citation: Huang, Y.H.,Liu, X.Y.,Du, X.X.,Jiang, Z.F.,Su, X.D.; The structural basis for the sensing and binding of cyclic di-GMP by STING; Nat.Struct.Mol.Biol., 19:728-730, 2012; PubMed: 22728659; DOI: 10.1038/nsmb.2333

Experimental method

X-RAY DIFFRACTION (2.601 Å)