4F5E
Crystal structure of ERIS/STING
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transmembrane protein 173 | polymer | 256 | 28623.4 | 1 | UniProt (Q86WV6) Pfam (PF15009) In PDB | Homo sapiens (human) | Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING |
2 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
3 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A: 141 - 379 (UniProt: Q86WV6)
PDB | External Database | Details |
---|---|---|
Gly 124 | - | expression tag |
Ser 125 | - | expression tag |
His 126 | - | expression tag |
Met 127 | - | expression tag |
Ala 128 | - | expression tag |
Ser 129 | - | expression tag |
Met 130 | - | expression tag |
Thr 131 | - | expression tag |
Gly 132 | - | expression tag |
Gly 133 | - | expression tag |
Met 134 | - | expression tag |
Gly 135 | - | expression tag |
Arg 136 | - | expression tag |
Gly 137 | - | expression tag |
Ser 138 | - | expression tag |
Met 139 | - | expression tag |
Met 140 | - | expression tag |
Ala 230 | Gly 230 | engineered mutation |
Arg 232 | His 232 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28623.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 238.3 | |
All* | Total formula weight | 28861.7 |