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2B5H
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BU of 2b5h by Molmil
1.5 A Resolution Crystal Structure of Recombinant R. Norvegicus Cysteine Dioxygenase
Descriptor: Cysteine dioxygenase type I, FE (III) ION
Authors:Simmons, C.R, Liu, Q, Huang, Q, Hao, Q, Begley, T.P, Karplus, P.A, Stipanuk, M.H.
Deposit date:2005-09-28
Release date:2006-04-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION.
J.Biol.Chem., 281, 2006
1KY4
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BU of 1ky4 by Molmil
S-Adenosylhomocysteine hydrolase refined with noncrystallographic restraints
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-adenosylhomocysteine hydrolase
Authors:Takata, Y, Takusagawa, F.
Deposit date:2002-02-03
Release date:2002-09-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Catalytic Mechanism of S-adenosylhomocysteine Hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
J.Biol.Chem., 277, 2002
5U9U
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BU of 5u9u by Molmil
De Novo Three-stranded Coiled Coil Peptide Containing a Tris-thiolate Site Engineered by D-Cysteine Ligands
Descriptor: Apo-(CoilSer L16(DCY))3, CHLORIDE ION, POLYETHYLENE GLYCOL (N=34), ...
Authors:Ruckthong, L, Stuckey, J.A, Pecoraro, V.L.
Deposit date:2016-12-18
Release date:2017-04-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils.
Chemistry, 23, 2017
2GH2
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BU of 2gh2 by Molmil
1.5 A Resolution R. Norvegicus Cysteine Dioxygenase Structure Crystallized in the Presence of Cysteine
Descriptor: Cysteine dioxygenase type I, FE (III) ION, SULFATE ION
Authors:Simmons, C.R, Karplus, P.A, Stipanuk, M.H.
Deposit date:2006-03-24
Release date:2006-04-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION.
J.Biol.Chem., 281, 2006
8JUI
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BU of 8jui by Molmil
Crystal structures of Cystathionine beta lyase from Bacillus cereus ATCC 14579
Descriptor: Cystathionine beta-lyase
Authors:Yu, H, Kim, K.-J.
Deposit date:2023-06-26
Release date:2024-07-03
Last modified:2024-12-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of cystathionine beta-lyase and cystathionine beta-lyase like protein from Bacillus cereus ATCC 14579.
Biochem.Biophys.Res.Commun., 742, 2024
4M3P
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BU of 4m3p by Molmil
Betaine-Homocysteine S-Methyltransferase from Homo sapiens complexed with Homocysteine
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Betaine--homocysteine S-methyltransferase 1, POTASSIUM ION, ...
Authors:Koutmos, M, Yamada, K, Mladkova, J, Paterova, J, Diamond, C.E, Tryon, K, Jungwirth, P, Garrow, T.A, Jiracek, J.
Deposit date:2013-08-06
Release date:2014-06-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Proteins, 82, 2014
1Z7W
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BU of 1z7w by Molmil
Crystal Structure of O-Acetylserine Sulfhydrylase from Arabidopsis thaliana
Descriptor: Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Bonner, E.R, Cahoon, R.E, Knapke, S.M, Jez, J.M.
Deposit date:2005-03-28
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis of Cysteine Biosynthesis in Plants: STRUCTURAL AND FUNCTIONAL ANALYSIS OF O-ACETYLSERINE SULFHYDRYLASE FROM ARABIDOPSIS THALIANA.
J.Biol.Chem., 280, 2005
3BM5
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BU of 3bm5 by Molmil
Crystal structure of O-acetyl-serine sulfhydrylase from Entamoeba histolytica in complex with cysteine
Descriptor: CYSTEINE, Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Krishna, C, Kumar, M, Kumar, S, Gourinath, S.
Deposit date:2007-12-12
Release date:2008-04-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase.
Proteins, 72, 2008
3DWG
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BU of 3dwg by Molmil
Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis
Descriptor: 9.5 kDa culture filtrate antigen cfp10A, Cysteine synthase B, PYRIDOXAL-5'-PHOSPHATE
Authors:Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E.
Deposit date:2008-07-22
Release date:2008-09-23
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
5I7R
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BU of 5i7r by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 2 [3-(3-([1,1'-biphenyl]-3-yl)ureido)benzoic acid]
Descriptor: 3-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}benzoic acid, ACETATE ION, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7H
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BU of 5i7h by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 6 [3-(3-(4-Bromophenyl)ureido)benzoic acid]
Descriptor: 3-{[(4-bromophenyl)carbamoyl]amino}benzoic acid, CHLORIDE ION, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-17
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7O
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BU of 5i7o by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 7 [3-(3-(4-Chlorophenyl)ureido)benzoic acid]
Descriptor: 3-{[(4-chlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I6D
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BU of 5i6d by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 5 [3-(3-(p-Tolyl)ureido) benzoic acid]
Descriptor: 3-{[(4-methylphenyl)carbamoyl]amino}benzoic acid, GLYCEROL, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-16
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7A
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BU of 5i7a by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 1 [3-(3-(3,4-Dichlorophenyl)ureido)benzoic acid]
Descriptor: 3-{[(3,4-dichlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-17
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IW8
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BU of 5iw8 by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 4 [5-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 5-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Brunner, K, Schnell, R, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IWC
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BU of 5iwc by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 3 [4-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 4-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Lindqvist, Y, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
8STW
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BU of 8stw by Molmil
K384N HUMAN CYSTATHIONINE BETA-SYNTHASE (delta 411-551)
Descriptor: Cystathionine beta-synthase, K384N variant, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Mascarenhas, R, Roman, J, Banerjee, R.
Deposit date:2023-05-11
Release date:2023-11-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Disease-causing cystathionine beta-synthase linker mutations impair allosteric regulation.
J.Biol.Chem., 299, 2023
2FQ6
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BU of 2fq6 by Molmil
Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide
Descriptor: Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER
Authors:Junop, M.S.
Deposit date:2006-01-17
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.
J.Med.Chem., 50, 2007
1CL1
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BU of 1cl1 by Molmil
CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI
Descriptor: BICARBONATE ION, CYSTATHIONINE BETA-LYASE
Authors:Clausen, T, Huber, R, Messerschmidt, A.
Deposit date:1997-09-02
Release date:1998-09-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.
J.Mol.Biol., 262, 1996
5OHX
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BU of 5ohx by Molmil
Structure of active cystathionine B-synthase from Apis mellifera
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
Authors:Gimenez-Mascarell, P, Majtan, T, Oyenarte, I, Ereno-Orbea, J, Majtan, J, Kraus, J.P, Klaudiny, J, Martinez-Cruz, L.A.
Deposit date:2017-07-18
Release date:2018-01-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of cystathionine beta-synthase from honeybee Apis mellifera.
J. Struct. Biol., 202, 2018
1QGN
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BU of 1qgn by Molmil
CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM
Descriptor: PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE
Authors:Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T.
Deposit date:1999-05-02
Release date:1999-08-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
J.Mol.Biol., 290, 1999
5XCN
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BU of 5xcn by Molmil
Crystal structure of M120A mutant of O-acetyl-L-serine sulfahydrylase from Haemophilus influenzae
Descriptor: Cysteine synthase
Authors:Abhishek, K, Kumaran, S.
Deposit date:2017-03-23
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Molecular Mechanism of Selective Substrate Engagement and Inhibitor Dis-engagement of Cysteine Synthase.
J.Biol.Chem., 2020
5XCW
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BU of 5xcw by Molmil
Crystal structure of M92A-M120A double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
Descriptor: Cysteine synthase
Authors:Abhishek, K, Kumaran, S.
Deposit date:2017-03-23
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Molecular Mechanism of Selective Substrate Engagement and Inhibitor Dis-engagement of Cysteine Synthase.
J.Biol.Chem., 2020
5XCP
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BU of 5xcp by Molmil
Crystal structure of M92A mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
Descriptor: Cysteine synthase
Authors:Abhishek, K, Kumaran, S.
Deposit date:2017-03-23
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Molecular Mechanism of Selective Substrate Engagement and Inhibitor Dis-engagement of Cysteine Synthase.
J.Biol.Chem., 2020
5B1H
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BU of 5b1h by Molmil
Crystal structure of cystathionine beta-synthase from Lactobacillus plantarum
Descriptor: Cystathionine beta-synthase, GLYCEROL, SULFATE ION
Authors:Matoba, Y, Sugiyama, M.
Deposit date:2015-12-04
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic and mutational analyses of cystathionine beta-synthase in the H2 S-synthetic gene cluster in Lactobacillus plantarum
Protein Sci., 26, 2017

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