PDB: 210 resultsInfo pagesStatus searchChemie searchBIRD

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7AA4	Structure of ClpC1-NTD bound to a CymA analogue Descriptor: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue Authors: Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. Deposit date: 2020-09-03 Release date: 2021-08-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.68 Å) Cite: BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
3TV6	Human B-Raf Kinase Domain in Complex with a Methoxypyrazolopyridinyl Benzamide Inhibitor Descriptor: 2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf Authors: Voegtli, W.C, Sturgis, H.L, Wu, W.-I. Deposit date: 2011-09-19 Release date: 2011-10-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors. ACS Med Chem Lett, 2, 2011
1E0E	N-terminal zinc-binding HHCC domain of HIV-2 integrase Descriptor: HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 INTEGRASE, ZINC ION Authors: Eijkelenboom, A.P.A.M, Van Den ent, F.M.I, Plasterk, R.H.A, Kaptein, R, Boelens, R. Deposit date: 2000-03-25 Release date: 2001-03-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Refined Solution Structure of the Dimeric N-Terminal Hhcc Domain of HIV-2 Integrase J.Biomol.NMR, 18, 2000
3FD7	Crystal structure of Onconase C87A/C104A-ONC Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ... Authors: Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T. Deposit date: 2008-11-25 Release date: 2009-12-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.531 Å) Cite: Impact of the C-terminal disulfide bond on the folding and stability of onconase. Chembiochem, 11, 2010
9ATV	X-ray co-crystal structure of NCGC00685960 / NCATS-SM9335 in NNMT Descriptor: (8M)-8-{3-[(3S)-1-(2-cyclohexylethyl)piperidin-3-yl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}quinolin-2(1H)-one, Nicotinamide N-methyltransferase Authors: Olland, A, White, A, Suto, R. Deposit date: 2024-02-27 Release date: 2025-03-05 Method: X-RAY DIFFRACTION (2.413 Å) Cite: NNMT inhibition blocks cancer-associated fibroblast-mediated immunosuppressi on To Be Published
9ARJ	CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum E1, major class Descriptor: Botulinum neurotoxin, Peptidase M27, Toxin Authors: Gao, L. Deposit date: 2024-02-23 Release date: 2025-01-22 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47. Nat.Struct.Mol.Biol., 32, 2025
9ARK	CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum E1, minor class Descriptor: Botulinum neurotoxin, Peptidase M27, Toxin Authors: Gao, L. Deposit date: 2024-02-23 Release date: 2025-01-22 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47. Nat.Struct.Mol.Biol., 32, 2025
9ARL	CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum strain A1-ST7B, major class Descriptor: Botulinum neurotoxin type A, NtnH, OrfX2 Authors: Gao, L. Deposit date: 2024-02-23 Release date: 2025-01-22 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (4 Å) Cite: Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47. Nat.Struct.Mol.Biol., 32, 2025
7Y43	Crystal structure of the KAT6A WH domain and its bound double stranded DNA Descriptor: DNA (5'-D(*GP*GP*AP*GP*TP*GP*CP*GP*CP*AP*CP*TP*CP*C)-3'), Histone acetyltransferase KAT6A, MAGNESIUM ION Authors: Wang, Z, Jia, Y. Deposit date: 2022-06-13 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain. Nucleic Acids Res., 51, 2023
4EIG	CA1698 camel antibody fragment in complex with DHFR Descriptor: CA1698 camel antibody fragment, Dihydrofolate reductase Authors: Oyen, D, Srinivasan, V. Deposit date: 2012-04-05 Release date: 2013-04-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
4EIZ	Structure of Nb113 bound to apoDHFR Descriptor: Dihydrofolate reductase, Nb113 Camel antibody fragment Authors: Oyen, D, Srinivasan, V. Deposit date: 2012-04-06 Release date: 2013-04-24 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
5O8D	Mutant of class II CPD photolyase from Methanosarcina mazei - Y345F Descriptor: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... Authors: Ignatz, E, Essen, L.-O. Deposit date: 2017-06-13 Release date: 2017-09-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Nicotinamide Adenine Dinucleotides Arrest Photoreduction of Class II DNA Photolyases in FADH ̇ State. Photochem. Photobiol., 94, 2018
4EJ1	Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex Descriptor: Dihydrofolate reductase, FOLIC ACID, Nb113 camelid antibody fragment, ... Authors: Oyen, D, Srinivasan, V. Deposit date: 2012-04-06 Release date: 2013-04-24 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
1O58	Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.80 A resolution Descriptor: O-acetylserine sulfhydrylase, PHOSPHATE ION Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2003-08-20 Release date: 2003-09-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution Proteins, 56, 2004
4FGV	Crystal structure of free CRM1 (crystal form 1) Descriptor: Chromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1) Authors: Monecke, T, Neumann, P, Dickmanns, A, Ficner, R. Deposit date: 2012-06-05 Release date: 2013-01-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.941 Å) Cite: Structural basis for cooperativity of CRM1 export complex formation. Proc.Natl.Acad.Sci.USA, 110, 2013
1O2D	Crystal structure of Alcohol dehydrogenase, iron-containing (TM0920) from Thermotoga maritima at 1.30 A resolution Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alcohol dehydrogenase, iron-containing, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2003-02-27 Release date: 2003-06-10 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution Proteins, 54, 2004
4FHB	Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179) Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Oyen, D. Deposit date: 2012-06-06 Release date: 2013-04-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... Authors: Bertram, K, Kastner, B. Deposit date: 2017-06-20 Release date: 2017-08-16 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017
5O86	Mutant of claas II CPD photolyase from Methanosarcina mazei - W388F Descriptor: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... Authors: Ignatz, E, Essen, L.-O. Deposit date: 2017-06-12 Release date: 2017-09-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.687 Å) Cite: Nicotinamide Adenine Dinucleotides Arrest Photoreduction of Class II DNA Photolyases in FADH ̇ State. Photochem. Photobiol., 94, 2018
2KB6	Solution structure of onconase C87A/C104A Descriptor: Protein P-30 Authors: Weininger, U, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Balbach, J. Deposit date: 2008-11-21 Release date: 2009-11-24 Last modified: 2024-10-30 Method: SOLUTION NMR Cite: Impact of the C-terminal disulfide bond on the folding and stability of onconase. Chembiochem, 11, 2010
2LFJ	Solution structure of the monomeric derivative of BS-RNase Descriptor: Seminal ribonuclease Authors: Spadaccini, R, Picone, D. Deposit date: 2011-07-06 Release date: 2012-02-08 Last modified: 2024-10-30 Method: SOLUTION NMR Cite: NMR Studies on Structure and Dynamics of the Monomeric Derivative of BS-RNase: New Insights for 3D Domain Swapping. Plos One, 7, 2012
7BL6	50S-ObgE-GMPPNP particle Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. Deposit date: 2021-01-18 Release date: 2021-05-12 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4 Å) Cite: Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
7BL2	pre-50S-ObgE particle state 1 Descriptor: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... Authors: Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. Deposit date: 2021-01-18 Release date: 2021-05-12 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
7BL3	pre-50S-ObgE particle state 2 Descriptor: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... Authors: Hilal, T, Nikolay, R, Spahn, C.M.T. Deposit date: 2021-01-18 Release date: 2021-05-12 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
7BL5	pre-50S-ObgE particle Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... Authors: Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S. Deposit date: 2021-01-18 Release date: 2021-05-12 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021

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