2JKZ
| SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (GUANOSINE 5'- MONOPHOSPHATE) (ORTHORHOMBIC CRYSTAL FORM) | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION | Authors: | Moynie, L, Giraud, M.F, Breton, A, Boissier, F, Daignan-Fornier, B, Dautant, A. | Deposit date: | 2008-09-02 | Release date: | 2009-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases. Protein Sci., 21, 2012
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2JBG
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6V01
| structure of human KCNQ1-KCNE3-CaM complex with PIP2 | Descriptor: | CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily E member 3, ... | Authors: | Mackinnon, R, Sun, J. | Deposit date: | 2019-11-18 | Release date: | 2019-12-04 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Basis of Human KCNQ1 Modulation and Gating. Cell, 180, 2020
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7KC0
| Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... | Authors: | Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. | Deposit date: | 2020-10-04 | Release date: | 2020-12-02 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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2JF2
| Nucleotide substrate binding by UDP-N-acetylglucosamine acyltransferase | Descriptor: | 1,2-ETHANEDIOL, ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE, DI(HYDROXYETHYL)ETHER | Authors: | Ulaganathan, V, Buetow, L, Hunter, W.N. | Deposit date: | 2007-01-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Nucleotide Substrate Recognition by Udp-N-Acetylglucosamine Acyltransferase (Lpxa) in the First Step of Lipid a Biosynthesis. J.Mol.Biol., 369, 2007
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2JB0
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2JF3
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7JNC
| cryo-EM structure of human proton-activated chloride channel PAC at pH 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel | Authors: | Lu, W, Ruan, R, Du, J. | Deposit date: | 2020-08-04 | Release date: | 2020-11-11 | Last modified: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Structures and pH-sensing mechanism of the proton-activated chloride channel. Nature, 588, 2020
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7WFC
| X-ray structure of HKU1-PLP2(Cys109Ser) catalytic mutant in complex with free ubiquitin | Descriptor: | 1,2-ETHANEDIOL, 60S ribosomal protein L40, Papain-like protease, ... | Authors: | Xiong, Y.X, Fu, Z.Y, Huang, H. | Deposit date: | 2021-12-26 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The substrate selectivity of papain-like proteases from human-infecting coronaviruses correlates with innate immune suppression. Sci.Signal., 16, 2023
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7BH2
| Cryo-EM Structure of KdpFABC in E2Pi state with BeF3 and K+ | Descriptor: | (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L. | Deposit date: | 2021-01-09 | Release date: | 2021-01-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for potassium transport in prokaryotes by KdpFABC. Proc.Natl.Acad.Sci.USA, 118, 2021
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5IS0
| Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 1, capsazepine | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-15 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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6YA9
| Crystal structure of rsGCaMP in the ON state (non-illuminated) | Descriptor: | CALCIUM ION, rsCGaMP | Authors: | Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D. | Deposit date: | 2020-03-11 | Release date: | 2021-10-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging. Nat.Biotechnol., 2021
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4WUM
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5IJL
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6Y95
| Ca2+-free Calmodulin mutant N53I | Descriptor: | Calmodulin | Authors: | Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | Deposit date: | 2020-03-06 | Release date: | 2020-04-29 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. J.Biol.Chem., 295, 2020
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5IRX
| Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc | Descriptor: | (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-14 | Release date: | 2016-05-25 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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6VAC
| Mouse retromer (VPS26/VPS35/VPS29) heterotrimer | Descriptor: | Vacuolar protein sorting-associated protein 26A, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | Authors: | Kendall, A.K, Jackson, L.P. | Deposit date: | 2019-12-17 | Release date: | 2020-02-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes. Structure, 28, 2020
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1PL5
| Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil | Descriptor: | Regulatory protein SIR4 | Authors: | Murphy, G.A, Spedale, E.J, Powell, S.T, Pillus, L, Schultz, S.C, Chen, L. | Deposit date: | 2003-06-06 | Release date: | 2004-06-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae. J.Mol.Biol., 334, 2003
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6BC8
| Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex | Descriptor: | ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ... | Authors: | Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. | Deposit date: | 2017-10-20 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7WKC
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6AX5
| RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1. | Descriptor: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | Authors: | Girvin, M.E, Cahill, S.M, Harris, R, Cowburn, D, Spira, M, Wu, X, Prakash, R, Bernowitz, M, Almo, S.C, Kalpana, G.V. | Deposit date: | 2017-09-06 | Release date: | 2017-10-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication. Nat Commun, 12, 2021
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7WXI
| GPR domain of Drosophila P5CS filament with glutamate and ATPgammaS | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXH
| GPR domain open form of Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7C09
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7WXG
| GPR domain closed form of Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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