7WFC

X-ray structure of HKU1-PLP2(Cys109Ser) catalytic mutant in complex with free ubiquitin

Summary for 7WFC

• Entry DOI: 10.2210/pdb7wfc/pdb
• Descriptor: Papain-like protease, 60S ribosomal protein L40, ZINC ION, ... (5 entities in total)
• Functional Keywords: hku1-plp2-ub complex, hydrolase
• Biological source: Human coronavirus HKU1; More
• Total number of polymer chains: 2
• Total formula weight: 43726.57

Authors

Xiong, Y.X.,Fu, Z.Y.,Huang, H. (deposition date: 2021-12-26, release date: 2022-12-28, Last modification date: 2023-11-29)

• Primary citation: Xiong, Y.,Huang, B.,Yang, Y.,Fu, X.,Fu, Z.,Xu, H.,Liu, M.,Cao, D.,Zhang, M.,Yang, H.,Niu, X.,Yu, C.,Huang, H.; The substrate selectivity of papain-like proteases from human-infecting coronaviruses correlates with innate immune suppression.; Sci.Signal., 16:eade1985-eade1985, 2023; PubMed: 37130166; DOI: 10.1126/scisignal.ade1985

Experimental method

X-RAY DIFFRACTION (2.6 Å)