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7KOX
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Alpha-7 nicotinic acetylcholine receptor bound to epibatidine and PNU-120596 in the activated state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Noviello, C.M, Hibbs, R.E, Gharpure, A, Mukhtasimova, N, Baxter, L, Cabuco, R, Borek, D, Sine, S.
Deposit date:2020-11-10
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor.
Cell, 184, 2021
7KOO
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Alpha-7 nicotinic acetylcholine receptor bound to alpha-bungarotoxin in a resting state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-bungarotoxin isoform V31, ...
Authors:Noviello, C.M, Hibbs, R.E, Gharpure, A, Mukhtasimova, N, Cabuco, R, Baxter, L, Borek, D, Sine, S.
Deposit date:2020-11-09
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor.
Cell, 184, 2021
7KOQ
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Alpha-7 nicotinic acetylcholine receptor bound to epibatidine in a desensitized state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Noviello, C.M, Hibbs, R.E, Gharpure, A, Mukhtasimova, N, Cabuco, R, Baxter, L, Borek, D, Sine, S.
Deposit date:2020-11-09
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor.
Cell, 184, 2021
6MRC
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BU of 6mrc by Molmil
ADP-bound human mitochondrial Hsp60-Hsp10 football complex
Descriptor: 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ...
Authors:Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I.
Deposit date:2018-10-12
Release date:2020-04-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.
Nat Commun, 11, 2020
2IJX
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BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
Descriptor: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-10-01
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
1K4Z
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BU of 1k4z by Molmil
C-terminal Domain of Cyclase Associated Protein
Descriptor: Adenylyl Cyclase-Associated Protein
Authors:Rozwarski, D.A, Fedorov, A.A, Dodatko, T, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-10-09
Release date:2002-03-13
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the actin binding domain of the cyclase-associated protein
Biochemistry, 43, 2004
6MU2
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BU of 6mu2 by Molmil
Structure of full-length IP3R1 channel in the Apo-state
Descriptor: Inositol 1,4,5-trisphosphate receptor type 1
Authors:Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
Deposit date:2018-10-22
Release date:2018-12-05
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
6B8P
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BU of 6b8p by Molmil
Crystal Structure of the Mg2+/CaM:Kv7.4 (KCNQ4) AB domain complex
Descriptor: Calmodulin-1, MAGNESIUM ION, Potassium voltage-gated channel subfamily KQT member 4, ...
Authors:Chang, A, Minor, D.L.
Deposit date:2017-10-09
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Calmodulin C-Lobe Ca
Neuron, 97, 2018
6VAC
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BU of 6vac by Molmil
Mouse retromer (VPS26/VPS35/VPS29) heterotrimer
Descriptor: Vacuolar protein sorting-associated protein 26A, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35
Authors:Kendall, A.K, Jackson, L.P.
Deposit date:2019-12-17
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes.
Structure, 28, 2020
7KL5
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BU of 7kl5 by Molmil
Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues: Phe4246 to Val4271
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Calmodulin-1, ...
Authors:Fisher, A.J, Ames, J.B, Yu, Q.
Deposit date:2020-10-29
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site.
Biochemistry, 60, 2021
2IPU
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BU of 2ipu by Molmil
PFA1 Fab fragment complexed with Abeta 1-8 peptide
Descriptor: ACETAMIDE, GLYCEROL, IgG2a Fab fragment Heavy Chain, ...
Authors:Gardberg, A.S, Dealwis, C.
Deposit date:2006-10-12
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
7QEP
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BU of 7qep by Molmil
Cryo-EM structure of the ribosome from Encephalitozoon cuniculi
Descriptor: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Nicholson, D, Ranson, N.A, Melnikov, S.V.
Deposit date:2021-12-03
Release date:2022-02-09
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
Nat Commun, 13, 2022
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
Descriptor: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5JD0
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BU of 5jd0 by Molmil
crystal structure of ARAP3 RhoGAP domain
Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Bao, H, Li, F, Wu, J, Shi, Y.
Deposit date:2016-04-15
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
6AX5
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BU of 6ax5 by Molmil
RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Authors:Girvin, M.E, Cahill, S.M, Harris, R, Cowburn, D, Spira, M, Wu, X, Prakash, R, Bernowitz, M, Almo, S.C, Kalpana, G.V.
Deposit date:2017-09-06
Release date:2017-10-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.
Nat Commun, 12, 2021
6Y78
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BU of 6y78 by Molmil
Structure of galectin-3C in complex with lactose determined by serial crystallography using a silicon nitride membrane support
Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hakansson, M, Welin, M, Shilova, A, Kovacic, R, Mueller, U, Logan, D.T.
Deposit date:2020-02-28
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
1K8F
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BU of 1k8f by Molmil
CRYSTAL STRUCTURE OF THE HUMAN C-TERMINAL CAP1-ADENYLYL CYCLASE ASSOCIATED PROTEIN
Descriptor: ADENYLYL CYCLASE-ASSOCIATED PROTEIN
Authors:Patskovsky, Y.V, Chance, M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-10-24
Release date:2003-07-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the actin binding domain of the cyclase-associated protein.
Biochemistry, 43, 2004
6N2M
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BU of 6n2m by Molmil
NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil
Descriptor: Caspase recruitment domain-containing protein 9, ZINC ION
Authors:Holliday, M.J, Fairbrother, W.J, Dueber, E.C.
Deposit date:2018-11-13
Release date:2019-07-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.
Nat Commun, 10, 2019
6BHN
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BU of 6bhn by Molmil
Red Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Descriptor: Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Yu, Q, Lim, S, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5MRW
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BU of 5mrw by Molmil
Structure of the KdpFABC complex
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Huang, C, Pedersen, B.P, Stokes, D.L.
Deposit date:2016-12-27
Release date:2017-06-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the potassium-importing KdpFABC membrane complex.
Nature, 546, 2017
5G1C
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BU of 5g1c by Molmil
Structure of HDAC like protein from Bordetella Alcaligenes bound the photoswitchable pyrazole Inhibitor CEW395
Descriptor: (2E)-N-hydroxy-3-{4-[(E)-(1,3,5-trimethyl-1H-pyrazol-4-yl)diazenyl]phenyl}prop-2-enamide, DI(HYDROXYETHYL)ETHER, HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE, ...
Authors:Kraemer, A, Meyer-Almes, F.J, Yildiz, O.
Deposit date:2016-03-24
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
ACS Infect Dis, 3, 2017
1I9E
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BU of 1i9e by Molmil
TCR DOMAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC TCELL VALPHA DOMAIN
Authors:Rudolph, M.G, Huang, M, Teyton, L, Wilson, I.A.
Deposit date:2001-03-19
Release date:2001-12-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.
J.Mol.Biol., 314, 2001
6VFF
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BU of 6vff by Molmil
Dimer of Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence derived from human GLI1 gene
Descriptor: Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5-R(*GP*CP*UP*CP*GP*CP*GP*AP*UP*GP*CP*UP*(8AZ)P*GP*AP*GP*GP*GP*CP* UP*CP*UP*GP*AP*UP*AP*GP*CP*UP*AP*CP*G)-3), ...
Authors:Thuy-boun, A.S, Fisher, A.J, Beal, P.A.
Deposit date:2020-01-03
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition.
Nucleic Acids Res., 48, 2020
1I38
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BU of 1i38 by Molmil
CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, ANDROGEN RECEPTOR
Authors:Sack, J.S.
Deposit date:2001-02-13
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
Proc.Natl.Acad.Sci.USA, 98, 2001
7WZS
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BU of 7wzs by Molmil
Crystal structure of Chromobacterium violaceum effector CopC in complex with host calmodulin and caspase-7
Descriptor: Calmodulin-1, Caspase-7, CopC
Authors:Ding, J.
Deposit date:2022-02-19
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases.
Mbio, 13, 2022

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