7KL5

Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues: Phe4246 to Val4271

Summary for 7KL5

• Entry DOI: 10.2210/pdb7kl5/pdb
• Descriptor: Calmodulin-1, Ryanodine receptor 2, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: calmodulin, cam, ryr2, cam binding domain, ryanodine receptor, metal binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 20953.91

Authors

Fisher, A.J.,Ames, J.B.,Yu, Q. (deposition date: 2020-10-29, release date: 2021-04-07, Last modification date: 2023-10-18)

• Primary citation: Yu, Q.,Anderson, D.E.,Kaur, R.,Fisher, A.J.,Ames, J.B.; The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site.; Biochemistry, 60:1088-1096, 2021; PubMed: 33754699; DOI: 10.1021/acs.biochem.1c00152

Experimental method

X-RAY DIFFRACTION (1.65 Å)