PDB: 72372 resultsInfo pagesStatus searchChemie searchBIRD

---

5V93	Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J. Deposit date: 2017-03-22 Release date: 2017-09-20 Last modified: 2020-08-12 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res., 45, 2017
6RNQ	Crystal structure of the dimerization domain of Gemin5 at 1.95 A Descriptor: Gem-associated protein 5, POTASSIUM ION Authors: Moreno-Morcillo, M, Ramon-Maiques, S, Martinez-Salas, E. Deposit date: 2019-05-09 Release date: 2019-11-27 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control. Nucleic Acids Res., 48, 2020
6CVO	Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... Authors: Schellenberg, M.J, Tumbale, P.P, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-08-29 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
5IJL	D-family DNA polymerase - DP2 subunit (catalytic subunit) Descriptor: DNA polymerase II large subunit, ZINC ION Authors: Sauguet, L, Raia, P, De Larue, M. Deposit date: 2016-03-02 Release date: 2016-08-31 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography. Nat Commun, 7, 2016
5NJV	Flavivirus NS5 domain Descriptor: CHLORIDE ION, NS5, S-ADENOSYLMETHIONINE Authors: Talapatra, S.K, Chatrin, C, Kozielski, F. Deposit date: 2017-03-29 Release date: 2018-01-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
5NJU	Flavivirus NS5 domain Descriptor: Genome polyprotein, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE Authors: Talapatra, S.K, Chatrin, C, Kozielski, F. Deposit date: 2017-03-29 Release date: 2018-01-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
5LQP	Cryo-EM reconstruction of bacteriophage AP205 virus-like particles. Descriptor: Coat protein Authors: Diebolder, C.A, Rumnieks, J, Tars, K, Koning, R.I. Deposit date: 2016-08-17 Release date: 2016-12-14 Last modified: 2019-10-23 Method: ELECTRON MICROSCOPY (6 Å) Cite: Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages. J. Mol. Biol., 428, 2016
8TXO	E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D. Deposit date: 2023-08-23 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Overcoming resolution attenuation during tilted cryo-EM data collection. Nat Commun, 15, 2024
5WWQ	Crystal structure of human NSun6 Descriptor: Putative methyltransferase NSUN6 Authors: Liu, R.J, Long, T, Wang, E.D. Deposit date: 2017-01-04 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.815 Å) Cite: Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6 Nucleic Acids Res., 45, 2017
2XSF	Crystal structure of the RRM domain of mouse Deleted in azoospermia- like Descriptor: DELETED IN AZOOSPERMIA-LIKE, GLYCEROL, SULFATE ION Authors: Jenkins, H.T, Edwards, T.A. Deposit date: 2010-09-28 Release date: 2011-10-05 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl Proc.Natl.Acad.Sci.USA, 108, 2011
5XJQ	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2/F/E/G from Human Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Yi, H, Zhang, R. Deposit date: 2017-05-04 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.28 Å) Cite: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
5HBM	Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase Descriptor: (7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MANGANESE (II) ION, ... Authors: Kirby, K.A, Sarafianos, S.G. Deposit date: 2015-12-31 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.043 Å) Cite: Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase To Be Published
5XJS	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E from Human Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Yi, H, Zhang, R. Deposit date: 2017-05-04 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.38 Å) Cite: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.808 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer Descriptor: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.34 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1	Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP Descriptor: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7QGI	Crystal structure of SARS-CoV-2 NSP14 in the absence of NSP10 Descriptor: PHOSPHATE ION, Proofreading exoribonuclease nsp14, ZINC ION Authors: Newman, J.A, Imprachim, N, Yosaatmadja, Y, Gileadi, O. Deposit date: 2021-12-08 Release date: 2022-01-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development. Nucleic Acids Res., 51, 2023
3IZQ	Structure of the Dom34-Hbs1-GDPNP complex bound to a translating ribosome Descriptor: Elongation factor 1 alpha-like protein, Protein DOM34 Authors: Becker, T, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Sieber, H, Abdel Motaal, B, Mielke, T, Berninghausen, O, Beckmann, R. Deposit date: 2010-11-30 Release date: 2011-06-01 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (9.5 Å) Cite: Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome. Nat.Struct.Mol.Biol., 18, 2011
5GSP	RIBONUCLEASE T1/3'-GMP, 9 WEEKS Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 Authors: Zegers, I, Wyns, L. Deposit date: 1997-12-09 Release date: 1998-03-18 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
2BZ2	Solution structure of NELF E RRM Descriptor: NEGATIVE ELONGATION FACTOR E Authors: Schweimer, K, Rao, J.N, Neumann, L, Rosch, P, Wohrl, B.M. Deposit date: 2005-08-10 Release date: 2006-08-16 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural studies on the RNA-recognition motif of NELF E, a cellular negative transcription elongation factor involved in the regulation of HIV transcription. Biochem. J., 400, 2006
6CVT	Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... Authors: Schellenberg, M.J, Tumbale, P.S, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.941 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVP	Human Aprataxin (Aptx) R199H bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... Authors: Schellenberg, M.J, Williams, R.S, Tumbale, P.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
4QUT	Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12 Descriptor: 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, Histone H4, ... Authors: Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2014-07-12 Release date: 2014-07-30 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells. J Mol Cell Biol, 8, 2016
8OPL	Virus-like Particle based on PVY coat protein with T43C and D136C mutation with helical architecture encapsidating ssRNA Descriptor: Genome polyprotein (Fragment), RNA (5'-R(P*UP*UP*UP*UP*U)-3') Authors: Kavcic, L, Kezar, A, Podobnik, M. Deposit date: 2023-04-07 Release date: 2024-01-24 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (2.41 Å) Cite: From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y. Commun Chem, 7, 2024
1FUU	YEAST INITIATION FACTOR 4A Descriptor: YEAST INITIATION FACTOR 4A Authors: Caruthers, J.M, Johnson, E.R, McKay, D.B. Deposit date: 2000-09-15 Release date: 2000-11-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase. Proc.Natl.Acad.Sci.USA, 97, 2000

<572573574575576577578579580581582583584585586587>