4QUT

Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12

Summary for 4QUT

• Entry DOI: 10.2210/pdb4qut/pdb
• Related: 4QUU
• Descriptor: ATPase family AAA domain-containing protein 2, Histone H4, SULFATE ION, ... (5 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, signaling protein, bromodomain, actyl-lysine binding, atpase family aaa domain-containing protein 2, epigenetics, histone, bromodomain-histone, structural genomics consortium (sgc)
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q6PL18 P62805
• Total number of polymer chains: 2
• Total formula weight: 16996.17

Authors

Chaikuad, A.,Felletar, I.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-12, release date: 2014-07-30, Last modification date: 2023-12-06)

• Primary citation: Morozumi, Y.,Boussouar, F.,Tan, M.,Chaikuad, A.,Jamshidikia, M.,Colak, G.,He, H.,Nie, L.,Petosa, C.,de Dieuleveult, M.,Curtet, S.,Vitte, A.L.,Rabatel, C.,Debernardi, A.,Cosset, F.L.,Verhoeyen, E.,Emadali, A.,Schweifer, N.,Gianni, D.,Gut, M.,Guardiola, P.,Rousseaux, S.,Gerard, M.,Knapp, S.,Zhao, Y.,Khochbin, S.; Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.; J Mol Cell Biol, 8:349-362, 2016; PubMed: 26459632; DOI: 10.1093/jmcb/mjv060

Experimental method

X-RAY DIFFRACTION (1.7 Å)