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5HBM

Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase

Summary for 5HBM
Entry DOI10.2210/pdb5hbm/pdb
DescriptorReverse transcriptase/ribonuclease H, p51 RT, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, ... (6 entities in total)
Functional Keywordstransferase, hydrolase, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceHuman immunodeficiency virus type 1 BH10 (HIV-1)
More
Total number of polymer chains2
Total formula weight114698.13
Authors
Kirby, K.A.,Sarafianos, S.G. (deposition date: 2015-12-31, release date: 2016-02-24, Last modification date: 2023-09-27)
Primary citationKirby, K.A.,Sarafianos, S.G.
Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.043 Å)
Structure validation

217705

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