7QGI
Crystal structure of SARS-CoV-2 NSP14 in the absence of NSP10
Summary for 7QGI
| Entry DOI | 10.2210/pdb7qgi/pdb |
| Descriptor | Proofreading exoribonuclease nsp14, ZINC ION, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | nuclease, methyltransferase, sars-cov-2, nsp14, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 59920.34 |
| Authors | Newman, J.A.,Imprachim, N.,Yosaatmadja, Y.,Gileadi, O. (deposition date: 2021-12-08, release date: 2022-01-26, Last modification date: 2024-02-07) |
| Primary citation | Imprachim, N.,Yosaatmadja, Y.,Newman, J.A. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development. Nucleic Acids Res., 51:475-487, 2023 Cited by PubMed: 36546776DOI: 10.1093/nar/gkac1207 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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