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8VG1
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BU of 8vg1 by Molmil
Cryo-EM structure of FoxA1 and GATA4 in complex with ALBN1 nucleosome
Descriptor: DNA (171-MER), Hepatocyte nuclear factor 3-alpha, Histone H2A type 1-B/E, ...
Authors:Zhou, B.R, Bai, Y.
Deposit date:2023-12-22
Release date:2024-08-07
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.
Mol.Cell, 84, 2024
8VFZ
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BU of 8vfz by Molmil
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 2)
Descriptor: DNA (171-MER), Hepatocyte nuclear factor 3-alpha, Histone H2A type 1-B/E, ...
Authors:Zhou, B.R, Bai, Y.
Deposit date:2023-12-22
Release date:2024-08-07
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.
Mol.Cell, 84, 2024
6M6B
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BU of 6m6b by Molmil
Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase and ATP-gamma-S
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Shi, J, Wen, A, Feng, Y.
Deposit date:2020-03-14
Release date:2020-10-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
7Q5B
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BU of 7q5b by Molmil
Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene
Descriptor: DNA (19-MER), DNA (31-MER), DNA (34-MER), ...
Authors:Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A.
Deposit date:2021-11-03
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Nat Commun, 12, 2021
6M6A
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BU of 6m6a by Molmil
Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Shi, J, Wen, A, Feng, Y.
Deposit date:2020-03-14
Release date:2020-10-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
7OZP
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BU of 7ozp by Molmil
RNA Polymerase II dimer (Class 3)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
7OZO
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BU of 7ozo by Molmil
RNA Polymerase II dimer (Class 2)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
6RCN
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BU of 6rcn by Molmil
Crystal structure of REXO2-D199A-dAdA
Descriptor: DNA (5'-D(P*AP*A)-3'), MAGNESIUM ION, Oligoribonuclease, ...
Authors:Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M.
Deposit date:2019-04-11
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
7ZWD
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BU of 7zwd by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-19
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX7
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BU of 7zx7 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX8
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BU of 7zx8 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-12-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7OZN
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BU of 7ozn by Molmil
RNA Polymerase II dimer (Class 1)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9
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BU of 8dy9 by Molmil
Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
7VWZ
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BU of 7vwz by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VWY
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BU of 7vwy by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
6YXU
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BU of 6yxu by Molmil
Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State I, primary channel engaged
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Kouba, T, Koval, T, Krasny, L, Dohnalek, J.
Deposit date:2020-05-03
Release date:2020-11-04
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase.
Nat Commun, 11, 2020
6YYS
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BU of 6yys by Molmil
Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State II, primary channel engaged and active site interfering
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Kouba, T, Koval, T, Krasny, L, Dohnalek, J.
Deposit date:2020-05-05
Release date:2020-11-04
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase.
Nat Commun, 11, 2020
7XUI
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BU of 7xui by Molmil
Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022
8X1V
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BU of 8x1v by Molmil
NMR structure of a bimolecular parallel G-quadruplex formed by AAGGG repeats from pathogenic RFC1 gene
Descriptor: DNA (5'-D(*AP*AP*GP*GP*GP*AP*AP*GP*GP*GP*AP*A)-3')
Authors:Wang, Y, Guo, P, Han, D.
Deposit date:2023-11-08
Release date:2024-01-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS.
Nucleic Acids Res., 52, 2024
7ZF2
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BU of 7zf2 by Molmil
Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R.
Deposit date:2022-03-31
Release date:2023-02-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization.
Nat Commun, 14, 2023
4C3H
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BU of 4c3h by Molmil
Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93
Descriptor: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ...
Authors:Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W.
Deposit date:2013-08-24
Release date:2013-10-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Crystal Structure of the 14-Subunit RNA Polymerase I
Nature, 502, 2013
6YOV
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BU of 6yov by Molmil
OCT4-SOX2-bound nucleosome - SHL+6
Descriptor: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2020-04-15
Release date:2020-05-06
Last modified:2020-07-08
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
8SYI
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BU of 8syi by Molmil
Cyanobacterial RNAP-EC
Descriptor: DNA (37-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Qayyum, M.Z, Imashimizu, M, Leanca, M, Vishwakarma, R.K, Bradley Riaz, A, Yuzenkova, Y, Murakami, K.S.
Deposit date:2023-05-25
Release date:2023-07-05
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024

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