7QJS
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![BU of 7qjs by Molmil](/molmil-images/mine/7qjs) | Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705) | Descriptor: | Cutinase 2, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Zahn, M, Shakespeare, T.J, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2021-12-17 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.429 Å) | Cite: | Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity Nat Commun, 13, 2022
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7R79
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![BU of 7r79 by Molmil](/molmil-images/mine/7r79) | Histoplasma capsulatum H88 Calcium Binding Protein 1 (Cbp1) | Descriptor: | Calcium-binding protein | Authors: | Herrera, N, Azimova, D, Sil, A, Rosenberg, O.S. | Deposit date: | 2021-06-24 | Release date: | 2022-04-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathog., 18, 2022
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6NKG
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![BU of 6nkg by Molmil](/molmil-images/mine/6nkg) | Crystal Structure of the Lipase Lip_vut5 from Goat Rumen metagenome. | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Lip_vut5, ... | Authors: | Kim, Y, Welk, L, Mukendi, G, Nkhi, G, Motloi, T, Jedrzejczak, R, Feto, N, Joachimiak, A. | Deposit date: | 2019-01-07 | Release date: | 2020-01-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of the Lipase Lip_vut5 from Goat Rumen metagenome. To Be Published
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6NQI
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![BU of 6nqi by Molmil](/molmil-images/mine/6nqi) | Prp8 RH domain from C. merolae | Descriptor: | BETA-MERCAPTOETHANOL, Pre-mRNA splicing factor PRP8 | Authors: | Garside, E.L, MacMillan, A.M. | Deposit date: | 2019-01-21 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa. J.Mol.Biol., 431, 2019
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5ZUN
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![BU of 5zun by Molmil](/molmil-images/mine/5zun) | Crystal structure of human monoacylglycerol lipase in complex with compound 3l | Descriptor: | (4R)-1-(2'-chloro[1,1'-biphenyl]-3-yl)-4-[4-(1,3-thiazole-2-carbonyl)piperazin-1-yl]pyrrolidin-2-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Sogabe, S, Zama, Y, Lane, W, Snell, G. | Deposit date: | 2018-05-08 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors J. Med. Chem., 61, 2018
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7AC1
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![BU of 7ac1 by Molmil](/molmil-images/mine/7ac1) | Solution structure of the TAF4-RST domain | Descriptor: | Transcription initiation factor TFIID subunit 4 | Authors: | Staby, L, Davidsen, R, Bugge, K, Skriver, K, Kragelund, B.B. | Deposit date: | 2020-09-09 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | alpha alpha-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes. J.Biol.Chem., 298, 2022
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6EIC
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![BU of 6eic by Molmil](/molmil-images/mine/6eic) | Crystal structure of Rv0183, a Monoglyceride Lipase from Mycobacterium Tuberculosis | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Mycobacterium Tuberculosis Monoglyceride Lipase, NITRATE ION, ... | Authors: | Aschauer, P, Pavkov-Keller, T, Oberer, M. | Deposit date: | 2017-09-19 | Release date: | 2018-06-27 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition. Sci Rep, 8, 2018
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3J9X
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![BU of 3j9x by Molmil](/molmil-images/mine/3j9x) | A Virus that Infects a Hyperthermophile Encapsidates A-Form DNA | Descriptor: | DNA, coat protein | Authors: | DiMaio, F, Yu, X, Rensen, E, Krupovic, M, Prangishvili, D, Egelman, E. | Deposit date: | 2015-03-21 | Release date: | 2015-06-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A virus that infects a hyperthermophile encapsidates A-form DNA. Science, 348, 2015
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6AID
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![BU of 6aid by Molmil](/molmil-images/mine/6aid) | Structural insights into the unique polylactate degrading mechanism of Thermobifida alba cutinase | Descriptor: | CALCIUM ION, Esterase, LACTIC ACID, ... | Authors: | Kitadokoro, K, Kakara, M, Matsui, S, Osokoshi, R, Thumarat, U, Kawai, F, Kamitani, S. | Deposit date: | 2018-08-22 | Release date: | 2019-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural insights into the unique polylactate-degrading mechanism of Thermobifida alba cutinase. Febs J., 286, 2019
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6B9M
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![BU of 6b9m by Molmil](/molmil-images/mine/6b9m) | |
6AX1
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![BU of 6ax1 by Molmil](/molmil-images/mine/6ax1) | Structure of human monoacylglycerol lipase bound to a covalent inhibitor | Descriptor: | 1,1,1,3,3,3-hexafluoropropan-2-yl 3-(3-phenyl-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate, GLYCEROL, Monoglyceride lipase | Authors: | Pandit, J. | Deposit date: | 2017-09-06 | Release date: | 2017-12-27 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. J. Med. Chem., 60, 2017
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3JW8
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![BU of 3jw8 by Molmil](/molmil-images/mine/3jw8) | Crystal structure of human mono-glyceride lipase | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, MGLL protein | Authors: | Bertrand, T, Auge, F, Houtmann, J, Rak, A, Vallee, F, Mikol, V, Berne, P.F, Michot, N, Cheuret, D, Hoornaert, C, Mathieu, M. | Deposit date: | 2009-09-18 | Release date: | 2010-01-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for human monoglyceride lipase inhibition. J.Mol.Biol., 396, 2010
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3JAC
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![BU of 3jac by Molmil](/molmil-images/mine/3jac) | Cryo-EM study of a channel | Descriptor: | Piezo-type mechanosensitive ion channel component 1 | Authors: | Ge, J, Li, W, Zhao, Q, Li, N, Xiao, B, Gao, N, Yang, M. | Deposit date: | 2015-06-05 | Release date: | 2015-09-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Architecture of the mammalian mechanosensitive Piezo1 channel Nature, 527, 2015
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3JWE
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![BU of 3jwe by Molmil](/molmil-images/mine/3jwe) | Crystal structure of human mono-glyceride lipase in complex with SAR629 | Descriptor: | 1-[bis(4-fluorophenyl)methyl]-4-(1H-1,2,4-triazol-1-ylcarbonyl)piperazine, MGLL protein | Authors: | Bertrand, T, Auge, F, Houtmann, J, Rak, A, Vallee, F, Mikol, V, Berne, P.F, Michot, N, Cheuret, D, Hoornaert, C, Mathieu, M. | Deposit date: | 2009-09-18 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for human monoglyceride lipase inhibition. J.Mol.Biol., 396, 2010
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6BZL
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![BU of 6bzl by Molmil](/molmil-images/mine/6bzl) | Solution structure of VEK75 | Descriptor: | M protein | Authors: | Qiu, C, Yuan, Y, Castellino, F.J. | Deposit date: | 2017-12-24 | Release date: | 2019-01-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization. J.Struct.Biol., 204, 2018
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6GCE
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![BU of 6gce by Molmil](/molmil-images/mine/6gce) | |
6BQ0
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![BU of 6bq0 by Molmil](/molmil-images/mine/6bq0) | Structure of human monoacylglycerol lipase bound to a covalent inhibitor | Descriptor: | 1-({(1R,5S,6r)-6-[1-(4-fluorophenyl)-1H-pyrazol-3-yl]-3-azabicyclo[3.1.0]hexane-3-carbonyl}oxy)pyrrolidine-2,5-dione, Monoglyceride lipase | Authors: | Pandit, J. | Deposit date: | 2017-11-27 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J. Med. Chem., 61, 2018
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6BZJ
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![BU of 6bzj by Molmil](/molmil-images/mine/6bzj) | Solution structure of AGL55 | Descriptor: | M protein | Authors: | Qiu, C, Yuan, Y, Castellino, F.J. | Deposit date: | 2017-12-24 | Release date: | 2019-01-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization. J.Struct.Biol., 204, 2018
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6GCF
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![BU of 6gcf by Molmil](/molmil-images/mine/6gcf) | |
6BZK
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![BU of 6bzk by Molmil](/molmil-images/mine/6bzk) | Solution structure of KTI55 | Descriptor: | M protein | Authors: | Castellino, F.J, Qiu, C, Yuan, Y. | Deposit date: | 2017-12-24 | Release date: | 2019-01-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization. J.Struct.Biol., 204, 2018
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6GCD
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![BU of 6gcd by Molmil](/molmil-images/mine/6gcd) | |
3HJU
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![BU of 3hju by Molmil](/molmil-images/mine/3hju) | Crystal structure of human monoglyceride lipase | Descriptor: | GLYCEROL, Monoglyceride lipase | Authors: | Labar, G, Bauvois, C, Borel, F, Ferrer, J.-L, Wouters, J, Lambert, D.M. | Deposit date: | 2009-05-22 | Release date: | 2009-12-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Human Monoacylglycerol Lipase, a Key Actor in Endocannabinoid Signaling Chembiochem, 11, 2010
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6ELV
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![BU of 6elv by Molmil](/molmil-images/mine/6elv) | Recombinantly expressed C-terminal domain of MdPPO1 (Csole-domain) | Descriptor: | CALCIUM ION, CHLORIDE ION, Polyphenol oxidase, ... | Authors: | Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. | Deposit date: | 2017-09-29 | Release date: | 2019-03-20 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase. Angew.Chem.Int.Ed.Engl., 58, 2019
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6ELT
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![BU of 6elt by Molmil](/molmil-images/mine/6elt) | C-terminal domain of MdPPO1 upon self-cleavage (Ccleaved-domain) | Descriptor: | CALCIUM ION, Polyphenol oxidase, chloroplastic | Authors: | Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. | Deposit date: | 2017-09-29 | Release date: | 2019-03-20 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase. Angew.Chem.Int.Ed.Engl., 58, 2019
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5LUK
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![BU of 5luk by Molmil](/molmil-images/mine/5luk) | Structure of a double variant of cutinase 2 from Thermobifida cellulosilytica | Descriptor: | CHLORIDE ION, Cutinase 2, MAGNESIUM ION | Authors: | Hromic, A, Lyskowski, A, Gruber, K. | Deposit date: | 2016-09-09 | Release date: | 2017-07-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica. Biotechnol. Bioeng., 114, 2017
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