Cryo-EM study of a channel

Summary for 3JAC

EMDB information6343
DescriptorPiezo-type mechanosensitive ion channel component 1 (1 entity in total)
Functional Keywordscryo-em, single particle, metal transport
Biological sourceMus musculus (mouse)
Total number of polymer chains3
Total molecular weight704502.33
Ge, J.,Li, W.,Zhao, Q.,Li, N.,Xiao, B.,Gao, N.,Yang, M. (deposition date: 2015-06-05, release date: 2015-09-23, Last modification date: 2015-11-25)
Primary citation
Ge, J.,Li, W.,Zhao, Q.,Li, N.,Chen, M.,Zhi, P.,Li, R.,Gao, N.,Xiao, B.,Yang, M.
Architecture of the mammalian mechanosensitive Piezo1 channel
Nature, 527:64-69, 2015
PubMed: 26390154 (PDB entries with the same primary citation)
DOI: 10.1038/nature15247
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers574.8%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3jac
no rotation
Molmil generated image of 3jac
rotated about x axis by 90°
Molmil generated image of 3jac
rotated about y axis by 90°