7R79
Histoplasma capsulatum H88 Calcium Binding Protein 1 (Cbp1)
Summary for 7R79
Entry DOI | 10.2210/pdb7r79/pdb |
Descriptor | Calcium-binding protein (2 entities in total) |
Functional Keywords | histoplasma, h88, fungal pathogenesis, secreted effector, macrophage lysis, cbp1, toxin |
Biological source | Ajellomyces capsulatus (Darling's disease fungus, Histoplasma capsulatum) |
Total number of polymer chains | 4 |
Total formula weight | 31615.35 |
Authors | Herrera, N.,Azimova, D.,Sil, A.,Rosenberg, O.S. (deposition date: 2021-06-24, release date: 2022-04-13, Last modification date: 2024-04-03) |
Primary citation | Azimova, D.,Herrera, N.,Duvenage, L.,Voorhies, M.,Rodriguez, R.A.,English, B.C.,Hoving, J.C.,Rosenberg, O.,Sil, A. Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathog., 18:e1010417-e1010417, 2022 Cited by PubMed: 35731824DOI: 10.1371/journal.ppat.1010417 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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