6GCD
DNA binding domain of restriction endonuclease McrBC in complex with 5-hydroxymethylcytosine DNA
Summary for 6GCD
| Entry DOI | 10.2210/pdb6gcd/pdb |
| Descriptor | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*(5HC)P*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5HC)P*CP*GP*GP*TP*CP*TP*C)-3'), ... (4 entities in total) |
| Functional Keywords | 5-hydroxymethylcytosine, restriction endonuclease, mcrbc, base flipping, dna binding protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 4 |
| Total formula weight | 46858.91 |
| Authors | Sasnauskas, G.,Manakova, E. (deposition date: 2018-04-17, release date: 2018-09-19, Last modification date: 2024-01-17) |
| Primary citation | Zagorskaite, E.,Manakova, E.,Sasnauskas, G. Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC. FEBS Lett., 592:3335-3345, 2018 Cited by PubMed: 30194838DOI: 10.1002/1873-3468.13244 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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