5WLN
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4JS0
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![BU of 4js0 by Molmil](/molmil-images/mine/4js0) | Complex of Cdc42 with the CRIB-PR domain of IRSp53 | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain-specific angiogenesis inhibitor 1-associated protein 2, Cell division control protein 42 homolog, ... | Authors: | Kast, D.J, Dominguez, R. | Deposit date: | 2013-03-22 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors. Nat.Struct.Mol.Biol., 21, 2014
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6I1Y
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![BU of 6i1y by Molmil](/molmil-images/mine/6i1y) | Vibrio vulnificus EpsD | Descriptor: | General secretion pathway protein GspD | Authors: | Contreras-Martel, C, Farias Estrozi, L. | Deposit date: | 2018-10-30 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system. Plos Pathog., 15, 2019
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1M1B
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![BU of 1m1b by Molmil](/molmil-images/mine/1m1b) | Crystal Structure of Phosphoenolpyruvate Mutase Complexed with Sulfopyruvate | Descriptor: | MAGNESIUM ION, PHOSPHOENOLPYRUVATE PHOSPHOMUTASE, SULFOPYRUVATE | Authors: | Liu, S, Lu, Z, Jia, Y, Dunaway-Mariano, D, Herzberg, O. | Deposit date: | 2002-06-18 | Release date: | 2002-08-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Dissociative phosphoryl transfer in PEP mutase catalysis: structure of the enzyme/sulfopyruvate complex and kinetic properties of mutants. Biochemistry, 41, 2002
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6I1X
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![BU of 6i1x by Molmil](/molmil-images/mine/6i1x) | Aeromonas hydrophila ExeD | Descriptor: | Type II secretion system protein D | Authors: | Contreras-Martel, C, Farias Estrozi, L. | Deposit date: | 2018-10-30 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system. Plos Pathog., 15, 2019
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6I2V
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![BU of 6i2v by Molmil](/molmil-images/mine/6i2v) | Pilotin from Vibrio vulnificus type 2 secretion system, EpsS. | Descriptor: | 1,2-ETHANEDIOL, PENTAETHYLENE GLYCOL, SULFATE ION, ... | Authors: | Howard, S.P, Estrozi, L, Bertrand, Q, Contreras-Martel, C, Strozen, T, Job, V, Martins, A, Fenel, D, Schoehn, G, Dessen, A. | Deposit date: | 2018-11-02 | Release date: | 2019-04-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system. Plos Pathog., 15, 2019
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4YDH
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![BU of 4ydh by Molmil](/molmil-images/mine/4ydh) | The structure of human FMNL1 N-terminal domains bound to Cdc42 | Descriptor: | Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ... | Authors: | Kuhn, S, Anand, K, Geyer, M. | Deposit date: | 2015-02-22 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nat Commun, 6, 2015
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1NF3
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![BU of 1nf3 by Molmil](/molmil-images/mine/1nf3) | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 | Descriptor: | G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... | Authors: | Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. | Deposit date: | 2002-12-12 | Release date: | 2003-03-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003
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4ITR
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1Q47
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![BU of 1q47 by Molmil](/molmil-images/mine/1q47) | Structure of the Semaphorin 3A Receptor-Binding Module | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin 3A | Authors: | Antipenko, A, Himanen, J.-P, van Leyen, K, Nardi-Dei, V, Lesniak, J, Barton, W.A, Rajashankar, K.R, Lu, M, Hoemme, C, Puschel, A, Nikolov, D. | Deposit date: | 2003-08-01 | Release date: | 2004-08-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the semaphorin-3A receptor binding module. Neuron, 39, 2003
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2QRZ
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![BU of 2qrz by Molmil](/molmil-images/mine/2qrz) | Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required | Descriptor: | Cell division control protein 42 homolog precursor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Phillips, M.J, Calero, G, Chan, B, Cerione, R.A. | Deposit date: | 2007-07-30 | Release date: | 2008-03-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42. J.Biol.Chem., 283, 2008
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5XYA
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![BU of 5xya by Molmil](/molmil-images/mine/5xya) | Crystal structure of a serine protease from Streptococcus species | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CALCIUM ION, Chemokine protease C, ... | Authors: | Jobichen, C, Sivaraman, J. | Deposit date: | 2017-07-06 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of ScpC, a virulence protease fromStreptococcus pyogenes, reveals the functional domains and maturation mechanism. Biochem. J., 475, 2018
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5XYR
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![BU of 5xyr by Molmil](/molmil-images/mine/5xyr) | Crystal structure of a serine protease from Streptococcus species | Descriptor: | CALCIUM ION, CHLORIDE ION, Chemokine protease C, ... | Authors: | Jobichen, C, Sivaraman, J. | Deposit date: | 2017-07-10 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of ScpC, a virulence protease fromStreptococcus pyogenes, reveals the functional domains and maturation mechanism. Biochem. J., 475, 2018
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5UPL
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3GCG
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![BU of 3gcg by Molmil](/molmil-images/mine/3gcg) | crystal structure of MAP and CDC42 complex | Descriptor: | Cell division control protein 42 homolog, L0028 (Mitochondria associated protein) | Authors: | Chai, J, Huang, Z, Feng, Y, Wu, X. | Deposit date: | 2009-02-22 | Release date: | 2009-07-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics Nat.Struct.Mol.Biol., 16, 2009
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7S0Y
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![BU of 7s0y by Molmil](/molmil-images/mine/7s0y) | Structures of TcdB in complex with Cdc42 | Descriptor: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zheng, L, Rongsheng, J, Peng, C. | Deposit date: | 2021-08-31 | Release date: | 2021-09-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B. Sci Adv, 7, 2021
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5UPK
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![BU of 5upk by Molmil](/molmil-images/mine/5upk) | CDC42 binds PAK4 via an extended GTPase-effector interface - 3 peptide: PAK4cat, PAK4-N45, CDC42 | Descriptor: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Ha, B.H, Boggon, T.J. | Deposit date: | 2017-02-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CDC42 binds PAK4 via an extended GTPase-effector interface. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2ODB
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![BU of 2odb by Molmil](/molmil-images/mine/2odb) | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) | Descriptor: | CHLORIDE ION, Human Cell Division Cycle 42 (CDC42), MAGNESIUM ION, ... | Authors: | Ugochukwu, E, Yang, X, Elkins, J, Soundararajan, M, Pike, A.C.W, Eswaran, J, Burgess, N, Debreczeni, J.E, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Gileadi, O, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2006-12-22 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) To be Published
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4BED
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![BU of 4bed by Molmil](/molmil-images/mine/4bed) | |
2OWL
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![BU of 2owl by Molmil](/molmil-images/mine/2owl) | Crystal structure of E. coli RdgC | Descriptor: | CALCIUM ION, Recombination-associated protein rdgC | Authors: | Briggs, G.S, McEwan, P.A, Yu, J, Moore, T, Emsley, J, Lloyd, R.G. | Deposit date: | 2007-02-16 | Release date: | 2007-03-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ring Structure of the Escherichia coli DNA-binding Protein RdgC Associated with Recombination and Replication Fork Repair. J.Biol.Chem., 282, 2007
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6AJ4
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6AJL
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![BU of 6ajl by Molmil](/molmil-images/mine/6ajl) | DOCK7 mutant I1836Y complexed with Cdc42 | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 | Authors: | Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
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2NGR
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![BU of 2ngr by Molmil](/molmil-images/mine/2ngr) | TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP. | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nassar, N, Hoffman, G, Clardy, J, Cerione, R. | Deposit date: | 1998-07-31 | Release date: | 1999-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5, 1998
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2WMN
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![BU of 2wmn by Molmil](/molmil-images/mine/2wmn) | Structure of the complex between DOCK9 and Cdc42-GDP. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-DIPHOSPHATE | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-07-02 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.391 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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2WM9
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![BU of 2wm9 by Molmil](/molmil-images/mine/2wm9) | Structure of the complex between DOCK9 and Cdc42. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GLYCEROL | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-06-30 | Release date: | 2009-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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