2ODB

The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)

Summary for 2ODB

Related1GRN
DescriptorHuman Cell Division Cycle 42 (CDC42), Serine/threonine-protein kinase PAK 6, CHLORIDE ION, ... (7 entities in total)
Functional Keywordssmall gtpase, crib, kinase, protein-protein complex, structural genomics, structural genomics consortium, sgc, protein binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q9NQU5
Cell membrane ; Lipid-anchor ; Cytoplasmic side  P60953
Total number of polymer chains2
Total molecular weight26306.32
Authors
Primary citation
Yang, X.,Ugochukwu, E.,Elkins, J.,Soundararajan, M.,Eswaran, J.,Pike, A.C.W.,Burgess, N.,Debreczeni, J.E.,Gileadi, O.,Knapp, S.,Doyle, D.
The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.235201.7%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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