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8R8P
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BU of 8r8p by Molmil
Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition
Descriptor: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-6-(4-methylpiperazin-1-yl)quinazoline, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Malard, F, Campagne, S.
Deposit date:2023-11-29
Release date:2024-03-06
Last modified:2024-05-22
Method:SOLID-STATE NMR
Cite:The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
6C2U
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BU of 6c2u by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7T2F
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BU of 7t2f by Molmil
Solution structure of the model HEEH mini protein homodimer HEEH_TK_rd5_0341
Descriptor: HEEH mini protein HEEH_TK_rd5_0341
Authors:Lemak, A, Houliston, S, Kim, T.-E, Martel, C, Rocklin, G.J, Arrowsmith, C.H.
Deposit date:2021-12-04
Release date:2022-10-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
Proc.Natl.Acad.Sci.USA, 119, 2022
6BP9
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BU of 6bp9 by Molmil
HSPB5 alpha-crystallin domain mutant R120G-ACD
Descriptor: Alpha-crystallin B chain
Authors:Rajagopal, P, Klevit, R.E.
Deposit date:2017-11-22
Release date:2018-11-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:HSPB5 alpha-crystallin domain mutant R120G-ACD
To Be Published
8P7G
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BU of 8p7g by Molmil
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
Descriptor: Paired mesoderm homeobox protein 2B
Authors:Russo, L, Diana, D, Fattorusso, R.
Deposit date:2023-05-30
Release date:2024-05-15
Last modified:2024-06-26
Method:SOLUTION NMR
Cite:Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Chem Sci, 15, 2024
6C2V
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BU of 6c2v by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3KVD
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BU of 3kvd by Molmil
Crystal structure of the Neisseria meningitidis Factor H binding protein, fHbp (GNA1870) at 2.0 A resolution
Descriptor: Lipoprotein
Authors:Cendron, L, Veggi, D, Girardi, E, Zanotti, G.
Deposit date:2009-11-30
Release date:2010-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Acta Crystallogr.,Sect.F, 67, 2011
8R63
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BU of 8r63 by Molmil
Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition
Descriptor: 5-(1~{H}-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Malard, F, Campagne, S.
Deposit date:2023-11-20
Release date:2024-03-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
2V1V
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BU of 2v1v by Molmil
3D STRUCTURE OF THE M8L MUTANT OF SQUASH TRYPSIN INHIBITOR CMTI-I
Descriptor: TRYPSIN INHIBITOR 1
Authors:Sledz, P, Bolewska, K, Bierzynski, A, Zhukov, I.
Deposit date:2007-05-30
Release date:2007-06-19
Last modified:2019-10-09
Method:SOLUTION NMR
Cite:Conservative mutation Met8 --> Leu affects the folding process and structural stability of squash trypsin inhibitor CMTI-I.
Protein Sci., 9, 2000
8QTQ
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BU of 8qtq by Molmil
Thermostable WW domain
Descriptor: WW domain
Authors:Kovermann, M, Thomas, F.
Deposit date:2023-10-13
Release date:2024-07-03
Method:SOLUTION NMR
Cite:Thermostable WW-Domain Scaffold to Design Functional beta-Sheet Miniproteins.
J.Am.Chem.Soc., 2024
2WZD
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BU of 2wzd by Molmil
The catalytically active fully closed conformation of human phosphoglycerate kinase K219A mutant in complex with ADP, 3PG and aluminium trifluoride
Descriptor: 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ...
Authors:Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
6CO4
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BU of 6co4 by Molmil
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1
Authors:Lu, X, Walters, K.J.
Deposit date:2018-03-11
Release date:2018-04-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.
Nat Commun, 8, 2017
6CPI
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BU of 6cpi by Molmil
Solution structure of SH3 domain from Shank1
Descriptor: SH3 and multiple ankyrin repeat domains protein 1
Authors:Ishida, H, Vogel, H.J.
Deposit date:2018-03-13
Release date:2018-08-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels.
FEBS Lett., 592, 2018
6CPK
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BU of 6cpk by Molmil
Solution structure of SH3 domain from Shank3
Descriptor: SH3 and multiple ankyrin repeat domains protein 3
Authors:Ishida, H, Vogel, H.J.
Deposit date:2018-03-13
Release date:2018-08-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels.
FEBS Lett., 592, 2018
6CL3
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BU of 6cl3 by Molmil
LyeTxI-b, a synthetic peptide derived from Lycosa erythrognatha spider venom, shows potent antibiotic activity, in vitro and in vivo
Descriptor: Toxin LyeTx 1
Authors:de Lima, M.E, dos Reis, P.V, Resende, J.M, Verly, R.M.
Deposit date:2018-03-01
Release date:2018-05-30
Method:SOLUTION NMR
Cite:LyeTxI-b, a Synthetic Peptide Derived FromLycosa erythrognathaSpider Venom, Shows Potent Antibiotic Activityin Vitroandin Vivo.
Front Microbiol, 9, 2018
6CPJ
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BU of 6cpj by Molmil
Solution structure of SH3 domain from Shank2
Descriptor: SH3 and multiple ankyrin repeat domains protein 2
Authors:Ishida, H, Vogel, H.J.
Deposit date:2018-03-13
Release date:2018-08-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels.
FEBS Lett., 592, 2018
6D2H
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BU of 6d2h by Molmil
Three-Dimensional Structures of [Phe3]Cm-p1 analogs
Descriptor: SER-ARG-PHE-GLU-LEU-ILE-VAL-HIS-GLN-ARG-NH2
Authors:Alves, E.S.F, Liao, L.M.
Deposit date:2018-04-13
Release date:2019-04-17
Method:SOLUTION NMR
Cite:Three-Dimensional Structures of Cm-p1 and [Phe 3]Cm-p1 analogs
To be Published
3IAP
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BU of 3iap by Molmil
E. coli (lacZ) beta-galactosidase (E416Q)
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
Authors:Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E.
Deposit date:2009-07-14
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry
Protein J., 29, 2010
6CUC
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BU of 6cuc by Molmil
Solution structure of double knot toxin (DkTx)
Descriptor: Tau-theraphotoxin-Hs1a
Authors:Ramanujam, V, Mobli, M.
Deposit date:2018-03-25
Release date:2019-03-27
Last modified:2024-04-24
Method:SOLUTION NMR
Cite:Structural Basis of the Bivalency of the TRPV1 Agonist DkTx.
Angew.Chem.Int.Ed.Engl., 63, 2024
6CFA
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BU of 6cfa by Molmil
peptide PaAMP1R3
Descriptor: peptide PaAMP1R3
Authors:Alves, E.S.F, Liao, L.M.
Deposit date:2018-02-14
Release date:2019-03-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Synthetic peptide PaAMP1R3
To be Published
7R6P
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BU of 7r6p by Molmil
Solution structure of peptide toxin MIITX2-Mg1a from the venom of the Australian giant red bull ant Myrmecia gulosa
Descriptor: U-myrmeciitoxin(02)-Mg1a
Authors:Chin, Y.K, Eagle, D, Bankala, K, Robinson, S.D.
Deposit date:2021-06-23
Release date:2022-02-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MJ3
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BU of 7mj3 by Molmil
Structure of Hact-4
Descriptor: Hact-4
Authors:Schmidt, C.A, Daly, N.L.
Deposit date:2021-04-19
Release date:2022-08-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Diversity of coral derived peptides
To Be Published
7NIP
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BU of 7nip by Molmil
titin N2A unique sequence (UN2A) core
Descriptor: Isoform 11 of Titin
Authors:Zhou, T, Kovermann, M, Fleming, J.R, Mayans, O.
Deposit date:2021-02-13
Release date:2021-03-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular Characterisation of Titin N2A and Its Binding of CARP Reveals a Titin/Actin Cross-linking Mechanism.
J.Mol.Biol., 433, 2021
7RUL
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BU of 7rul by Molmil
I5R8 Mastoparano is a peptide synthetic, modified of Mastoparano (extracted from wasp venom)
Descriptor: Mastoparan-L peptide
Authors:Alves, E.S.F, Santos, B.P.O.
Deposit date:2021-08-17
Release date:2022-08-31
Method:SOLUTION NMR
Cite:Mastoparan I5R8, peptide antiviral derived of Mastoparan, venenon vesp.
To Be Published
7PMP
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BU of 7pmp by Molmil
Solution structure of Legionella pneumophila LspD
Descriptor: Type II protein secretion LspD
Authors:Portlock, T.J, Garnett, J.A.
Deposit date:2021-09-02
Release date:2022-09-14
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of Legionella pneumophila LspD N0
To Be Published

223790

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