6CO4

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets

Replaces:  2NBK

Summary for 6CO4

• Entry DOI: 10.2210/pdb6co4/pdb
• NMR Information: BMRB: 25979
• Descriptor: Proteasomal ubiquitin receptor ADRM1, 26S proteasome non-ATPase regulatory subunit 1 (2 entities in total)
• Functional Keywords: ubiquitin receptor binding, proteasome scaffolding protein, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 19043.38

Authors

Lu, X.,Walters, K.J. (deposition date: 2018-03-11, release date: 2018-04-04, Last modification date: 2023-06-14)

• Primary citation: Lu, X.,Nowicka, U.,Sridharan, V.,Liu, F.,Randles, L.,Hymel, D.,Dyba, M.,Tarasov, S.G.,Tarasova, N.I.,Zhao, X.Z.,Hamazaki, J.,Murata, S.,Burke, T.R.,Walters, K.J.; Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.; Nat Commun, 8:15540-, 2017; PubMed: 28598414; DOI: 10.1038/ncomms15540

Experimental method

SOLUTION NMR