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6CO4

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets

Replaces:  2NBK
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proteasomal ubiquitin receptor ADRM1polymer15417040.31UniProt (Q16186)
Pfam (PF04683)
Homo sapiens (Human)110 kDa cell membrane glycoprotein,Gp110,Adhesion-regulating molecule 1,ARM-1,Proteasome regulatory particle non-ATPase 13,hRpn13,Rpn13 homolog
2B
(B)
26S proteasome non-ATPase regulatory subunit 1polymer182003.01UniProt (Q99460)Homo sapiens (Human)26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112
Sequence modifications
A: 1 - 150 (UniProt: Q16186)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
B: 940 - 953 (UniProt: Q99460)
PDBExternal DatabaseDetails
Gly 936-expression tag
Pro 937-expression tag
Gly 938-expression tag
Ser 939-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight19043.4
All*Total formula weight19043.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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