4R2C
 
 | | Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA | | Descriptor: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Early growth response protein 1, ... | | Authors: | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2014-08-11 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
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4R2S
 | | Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | | Authors: | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2014-08-12 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.489 Å) | | Cite: | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
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4R2Q
 | | Wilms Tumor Protein (WT1) zinc fingers in complex with formylated DNA | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5FC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | | Authors: | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2014-08-12 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
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2RV2
 | | Solution structures of the DNA-binding domain (ZF14) of immune-related zinc-finger protein ZFAT | | Descriptor: | ZINC ION, Zinc finger protein ZFAT | | Authors: | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | Deposit date: | 2015-01-26 | | Release date: | 2015-04-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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8CUC
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8E3D
 | | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#11) | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*AP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*AP*T)-3'), ... | | Authors: | Horton, J.R, Ren, R, Cheng, X. | | Deposit date: | 2022-08-17 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
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8E3E
 | | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10) | | Descriptor: | DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ZINC ION, ... | | Authors: | Horton, J.R, Ren, R, Cheng, X. | | Deposit date: | 2022-08-17 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
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8DTN
 | | The complex of nanobody 6101 with BCL11A ZF6 | | Descriptor: | B-cell lymphoma/leukemia 11A, MAGNESIUM ION, Nanobody 6101, ... | | Authors: | Yin, M, Tenglin, K, Zhai, L, Dassama, L.M, Orkin, S.H. | | Deposit date: | 2022-07-26 | | Release date: | 2023-02-01 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | Evolution of nanobodies specific for BCL11A.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DTU
 | | The complex of nanobody 5344N74D with BCL11A ZF6. | | Descriptor: | B-cell lymphoma/leukemia 11A, Nanobody 5344N74D, ZINC ION | | Authors: | Yin, M, Tenglin, K, Zhai, L, Dassama, L.M, Orkin, S.H. | | Deposit date: | 2022-07-26 | | Release date: | 2023-02-01 | | Method: | X-RAY DIFFRACTION (2.447 Å) | | Cite: | Evolution of nanobodies specific for BCL11A.
Proc.Natl.Acad.Sci.USA, 120, 2023
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2WBS
 | | Crystal structure of the zinc finger domain of Klf4 bound to its target DNA | | Descriptor: | 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', GLYCEROL, ... | | Authors: | Zocher, G, Schuetz, A, Carstanjen, D, Heinemann, U. | | Deposit date: | 2009-03-03 | | Release date: | 2010-04-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
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2WBU
 | | CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA | | Descriptor: | 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', KRUEPPEL-LIKE FACTOR 4, ... | | Authors: | Schuetz, A, Zocher, G, Carstanjen, D, Heinemann, U. | | Deposit date: | 2009-03-05 | | Release date: | 2010-04-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
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2RUT
 | | Solution structures of the DNA-binding domain (ZF2) of immune-related zinc-finger protein ZFAT | | Descriptor: | ZINC ION, Zinc finger protein ZFAT | | Authors: | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | Deposit date: | 2015-01-26 | | Release date: | 2015-04-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT.
J Struct Funct Genomics, 16, 2015
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2RV3
 | | Solution structures of the DNA-binding domain (ZF15) of immune-related zinc-finger protein ZFAT | | Descriptor: | ZINC ION, Zinc finger protein ZFAT | | Authors: | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | Deposit date: | 2015-01-26 | | Release date: | 2015-04-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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1SP2
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1SP1
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8THO
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1X5W
 | | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2 | | Descriptor: | ZINC ION, Zinc finger protein 64, isoforms 1 | | Authors: | Yoneyama, M, Koshiba, S, Tochio, N, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-17 | | Release date: | 2005-11-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2
To be Published
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1X6H
 | | Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF | | Descriptor: | Transcriptional repressor CTCF, ZINC ION | | Authors: | Sato, M, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-17 | | Release date: | 2005-11-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF
To be Published
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1TF3
 | | TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES | | Descriptor: | 5S RNA GENE, TRANSCRIPTION FACTOR IIIA, ZINC ION | | Authors: | Foster, M.P, Wuttke, D.S, Radhakrishnan, I, Case, D.A, Gottesfeld, J.M, Wright, P.E. | | Deposit date: | 1997-07-01 | | Release date: | 1997-09-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA.
Nat.Struct.Biol., 4, 1997
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1XF7
 | | High Resolution NMR Structure of the Wilms' Tumor Suppressor Protein (WT1) Finger 3 | | Descriptor: | Wilms' Tumor Protein, ZINC ION | | Authors: | Lachenmann, M.J, Ladbury, J.E, Dong, J, Huang, K, Carey, P, Weiss, M.A. | | Deposit date: | 2004-09-14 | | Release date: | 2004-12-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity
Biochemistry, 43, 2004
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7MC3
 | | Solution structure of Miz-1 zinc finger 12 | | Descriptor: | Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION | | Authors: | Boisvert, O, Lavigne, P. | | Deposit date: | 2021-04-01 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
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7MC1
 | | Solution structure of Miz-1 Zinc finger 10 | | Descriptor: | Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION | | Authors: | Boisvert, O, Lavigne, P. | | Deposit date: | 2021-04-01 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
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7MC2
 | | Solution structure of Miz-1 Zinc finger 11 H586Y | | Descriptor: | Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION | | Authors: | Boisvert, O, Lavigne, P. | | Deposit date: | 2021-04-01 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
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1U86
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9AZI
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