PDB: 45953 resultsInfo pagesStatus searchChemie searchBIRD

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8SQU	Monomeric MapSPARTA bound with guide RNA and target DNA hybrid Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ... Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2023-05-04 Release date: 2023-08-23 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
4U0Y	Crystal structure of the DNA-binding domains of YvoA in complex with palindromic operator DNA Descriptor: CHLORIDE ION, DNA (5'-D(P*GP*TP*GP*GP*TP*CP*TP*AP*GP*AP*CP*CP*AP*CP*T)-3'), HTH-type transcriptional repressor YvoA Authors: Fillenberg, S.B, Muller, Y.A. Deposit date: 2014-07-14 Release date: 2015-01-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR. Nucleic Acids Res., 43, 2015
4UZC	KSHV LANA (ORF73) C-terminal domain, spiral: hexagonal crystal form Descriptor: ORF 73 Authors: Hellert, J, Krausze, J, Luhrs, T. Deposit date: 2014-09-05 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.7 Å) Cite: The 3D Structure of Kaposi Sarcoma Herpesvirus Lana C-Terminal Domain Bound to DNA. Proc.Natl.Acad.Sci.USA, 112, 2015
7CUI	Crystal structure of fission yeast Pot1 and Tpz1 Descriptor: Protection of telomeres protein 1, Protection of telomeres protein tpz1, SULFATE ION Authors: Sun, H, Wu, Z, Wu, J, Lei, M. Deposit date: 2020-08-23 Release date: 2021-08-25 Last modified: 2022-09-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
8SOK	Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... Authors: Cai, S.W. Deposit date: 2023-04-28 Release date: 2023-06-07 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: POT1 recruits and regulates CST-Pol alpha /Primase at human telomeres. Biorxiv, 2023
8SV6	Structure of the M. smegmatis DarR protein Descriptor: Fatty acid metabolism regulator protein Authors: Schumacher, M.A. Deposit date: 2023-05-15 Release date: 2023-11-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.56 Å) Cite: Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding. Nat Commun, 14, 2023
7CQ2	Crystal structure of Slx1-Slx4 Descriptor: GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ... Authors: Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. Deposit date: 2020-08-08 Release date: 2021-06-16 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
7CQ3	Crystal structure of Slx1-Slx4 Descriptor: SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ... Authors: Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. Deposit date: 2020-08-08 Release date: 2021-06-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.449 Å) Cite: Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
7DEP	S. aureus SsbB with 5-FU Descriptor: 5-FLUOROURACIL, Single-stranded DNA-binding protein Authors: Lin, E.S, Huang, Y.H, Huang, C.Y. Deposit date: 2020-11-04 Release date: 2020-12-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.094 Å) Cite: Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
7D8J	S. aureus SsbB with 5-FU Descriptor: 5-FLUOROURACIL, Single-stranded DNA-binding protein Authors: Lin, E.S, Huang, Y.H, Huang, C.Y. Deposit date: 2020-10-08 Release date: 2020-12-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
6DEG	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-05-11 Release date: 2018-05-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 To Be Published
4O68	Structure of human cyclic GMP-AMP synthase (cGAS) Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.436 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
4O67	Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.444 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
4O69	Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion Descriptor: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.252 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
3U05	Crystal structure of DB1804-D(CGCGAATTCGCG)2 complex Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole, MAGNESIUM ION Authors: Wei, D.G, Neidle, S. Deposit date: 2011-09-28 Release date: 2012-09-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster. J.Am.Chem.Soc., 135, 2013
4OFA	Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis Descriptor: 12-mer DNA(G), 12-mer DNA(T), MAGNESIUM ION, ... Authors: Ouzon-Shubeita, H, Lin, Y.-L, Lee, S. Deposit date: 2014-01-14 Release date: 2015-04-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of MBD4 bound to G:T mispair DNA To be Published
8SP3	Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ... Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2023-05-01 Release date: 2023-08-23 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
8SP0	Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ... Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2023-05-01 Release date: 2023-08-23 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
6D47	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-04-17 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum To Be Published
3KU0	Structure of GAP31 with adenine at its binding pocket Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein gelonin Authors: Kong, X.-P. Deposit date: 2009-11-26 Release date: 2010-01-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun., 391, 2010
3KO2	I-MsoI re-designed for altered DNA cleavage specificity (-7C) Descriptor: 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*GP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*CP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... Authors: Taylor, G.K, Stoddard, B.L. Deposit date: 2009-11-13 Release date: 2010-05-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
7CUJ	Crystal structure of fission yeast Ccq1 and Tpz1 Descriptor: Coiled-coil quantitatively-enriched protein 1, Protection of telomeres protein tpz1 Authors: Sun, H, Wu, Z, Wu, J, Lei, M. Deposit date: 2020-08-23 Release date: 2021-08-25 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
4FHC	Spore photoproduct lyase Descriptor: 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... Authors: Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. Deposit date: 2012-06-06 Release date: 2012-07-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res., 40, 2012
7COW	353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0 Descriptor: CALCIUM ION, CHLORIDE ION, DNA (353-MER), ... Authors: Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. Deposit date: 2020-08-05 Release date: 2021-08-11 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
2GAJ	Structure of Full Length Topoisomerase I from Thermotoga maritima in monoclinic crystal form Descriptor: DNA topoisomerase I Authors: Hansen, G. Deposit date: 2006-03-09 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of Full Length Topoisomerase I from Thermotoga maritima J.Mol.Biol., 358, 2006

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