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5CJ5
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BU of 5cj5 by Molmil
Structure of Mycobacterium thermoresistibile GlgE APO form at 3.13A resolution
Descriptor: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015
6MOF
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BU of 6mof by Molmil
Monomeric DARPin G2 complex with EpoR
Descriptor: 1,2-ETHANEDIOL, Erythropoietin receptor, G2 DARPin
Authors:Jude, K.M, Mohan, K, Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOR
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BU of 6mor by Molmil
Crystal Structure of the All-Trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121Y Mutant of Human Cellular Retinoic Acid Binding Protein II in the Dark at 1.79 Angstrom Resolution
Descriptor: Cellular retinoic acid-binding protein 2, RETINAL
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-10-04
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Mimicking Microbial Rhodopsin Isomerization in a Single Crystal.
J. Am. Chem. Soc., 141, 2019
6MQW
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BU of 6mqw by Molmil
Crystal Structure of All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121E Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm laser (30 seconds) and subsequently dark adapted (10 minutes) at 2.1 Angstrom Resolution
Descriptor: Cellular retinoic acid-binding protein 2, RETINAL
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-10-11
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Mimicking Microbial Rhodopsin Isomerization in a Single Crystal.
J. Am. Chem. Soc., 141, 2019
6D39
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BU of 6d39 by Molmil
Photodissociable dimeric Dronpa green fluorescent protein variant V (pdDronpaV)
Descriptor: Fluorescent protein Dronpa, SULFATE ION
Authors:Zhou, X, Fan, L, Lin, M.
Deposit date:2018-04-15
Release date:2018-05-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Optical control of cell signaling by single-chain photoswitchable kinases.
Science, 355, 2017
5CGM
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BU of 5cgm by Molmil
Structure of Mycobacterium thermoresistibile GlgE in complex with maltose at 1.95A resolution
Descriptor: 1,2-ETHANEDIOL, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, CHLORIDE ION, ...
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-09
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015
3K73
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BU of 3k73 by Molmil
Crystal Structure of Phosphate bound Holo Glyceraldehyde-3-phosphate dehydrogenase 1 from MRSA252 at 2.5 Angstrom resolution
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
Authors:Mukherjee, S, Dutta, D, Saha, B, Das, A.K.
Deposit date:2009-10-12
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism.
J.Mol.Biol., 401, 2010
5CIM
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BU of 5cim by Molmil
Structure of Mycobacterium thermoresistibile GlgE in complex with maltose (cocrystallisation with maltose-1-phosphate) at 3.32A resolution
Descriptor: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015
6CL1
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BU of 6cl1 by Molmil
Caspase-7 in complex with Ac-DW3-KE
Descriptor: ACE-1MH-ASP-B3L-PHE-1U8, Caspase-7 subunit p11, Caspase-7 subunit p20
Authors:Solania, A.T, Gonzalez-Paez, G.E, Wolan, D.W.
Deposit date:2018-03-01
Release date:2019-03-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
Acs Chem.Biol., 14, 2019
6NIP
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BU of 6nip by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, MZ1 Heavy chain, MZ1 Light Chain
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-12-31
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.16 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
3KAR
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BU of 3kar by Molmil
THE MOTOR DOMAIN OF KINESIN-LIKE PROTEIN KAR3, A SACCHAROMYCES CEREVISIAE KINESIN-RELATED PROTEIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION
Authors:Gulick, A.M, Song, H, Endow, S, Rayment, I.
Deposit date:1997-11-26
Release date:1998-04-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution.
Biochemistry, 37, 1998
3JVS
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BU of 3jvs by Molmil
Characterization of the Chk1 allosteric inhibitor binding site
Descriptor: 2-[(4-tert-butyl-3-nitrophenyl)carbonyl]-N-naphthalen-1-ylhydrazinecarboxamide, Serine/threonine-protein kinase Chk1
Authors:Chen, P.
Deposit date:2009-09-17
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of the CHK1 allosteric inhibitor binding site.
Biochemistry, 48, 2009
3JZ1
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BU of 3jz1 by Molmil
Crystal structure of human thrombin mutant N143P in E:Na+ form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NITRATE ION, ...
Authors:Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
Deposit date:2009-09-22
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
6NKP
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BU of 6nkp by Molmil
EphA2 LBD in complex with bA-WLA-YSKbio peptide
Descriptor: BIOTIN, Ephrin type-A receptor 2, bA-WLA-YSKbio peptide
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-07
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
5LWY
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BU of 5lwy by Molmil
Revised crystal structure of the human adiponectin receptor 2 in complex with a C18 free fatty acid
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, GLYCEROL, ...
Authors:Leyrat, C, Vasiliauskaite-Brooks, I, Granier, S.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
6FRX
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BU of 6frx by Molmil
PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ~{N}-[3-[(5-chloranyl-2-phenylazanyl-pyrimidin-4-yl)amino]phenyl]prop-2-enamide
Authors:Engh, R.A, Kazi, A.A.
Deposit date:2018-02-16
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor
To Be Published
6G56
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BU of 6g56 by Molmil
Apo-structure of the alanine racemase from Staphylococcus aureus
Descriptor: Alanine racemase 1, GLYCEROL, SULFATE ION
Authors:Hoegl, A, Sieber, S.A, Schneider, S.
Deposit date:2018-03-29
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10, 2018
5M51
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BU of 5m51 by Molmil
Nek2 bound to arylaminopurine compound 8
Descriptor: 3-[[6-(cyclohexylmethoxy)-9~{H}-purin-2-yl]amino]benzamide, Serine/threonine-protein kinase Nek2
Authors:Bayliss, R, Yeoh, S.
Deposit date:2016-10-20
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
5M53
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BU of 5m53 by Molmil
Nek2 bound to arylaminopurine inhibitor 11
Descriptor: 1,2-ETHANEDIOL, 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Bayliss, R, Carr, K.H.
Deposit date:2016-10-20
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
6NJZ
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BU of 6njz by Molmil
EphA2 LBD in complex with YSA-GSGSK-bio peptide
Descriptor: BIOTIN, Ephrin type-A receptor 2, GLYCEROL, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-04
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
5CR6
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BU of 5cr6 by Molmil
Structure of pneumolysin at 1.98 A resolution
Descriptor: Pneumolysin
Authors:Marshall, J.E, Faraj, B.H.A, Gingras, A.R, Lonnen, R, Sheikh, M.A, El-Mezgueldi, M, Moody, P.C.E, Andrew, P.W, Wallis, R.
Deposit date:2015-07-22
Release date:2015-09-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Crystal Structure of Pneumolysin at 2.0 angstrom Resolution Reveals the Molecular Packing of the Pre-pore Complex.
Sci Rep, 5, 2015
2BNQ
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BU of 2bnq by Molmil
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
5CTT
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BU of 5ctt by Molmil
Crystal structure of human SART3/TIP110 NLS-mouse importin alpha complex
Descriptor: Importin subunit alpha-1, Squamous cell carcinoma antigen recognized by T-cells 3
Authors:Park, J.K, Kim, E.E.
Deposit date:2015-07-24
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3
Nucleic Acids Res., 44, 2016
6G5Q
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BU of 6g5q by Molmil
The structure of a carbohydrate active P450
Descriptor: 6-O-methyl-beta-D-galactopyranose, Cytochrome P450, GLYCEROL, ...
Authors:Robb, C.S, Hehemann, J.H.
Deposit date:2018-03-29
Release date:2018-11-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases.
Biochem. J., 475, 2018
7VGA
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BU of 7vga by Molmil
Cryo-EM structure of alphavirus, Getah virus
Descriptor: Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Wang, M, Sun, Z.Z, Wang, J.F.
Deposit date:2021-09-15
Release date:2022-11-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Implications for the pathogenicity and antigenicity of alpha viruses revealed by a 3.5 angstrom Cryo-EM structure of Getah virus
To Be Published

222624

건을2024-07-17부터공개중

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