PDB: 72678 resultsInfo pagesStatus searchChemie searchBIRD

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8UYK	MERS 5' proximal stem-loop 5, conformation 1 Descriptor: MERS 5' proximal stem-loop 5 Authors: Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. Deposit date: 2023-11-13 Release date: 2023-12-06 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
8UYG	BtCoV-HKU5 5' proximal stem-loop 5, conformation 2 Descriptor: RNA (135-MER) Authors: Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. Deposit date: 2023-11-13 Release date: 2023-12-06 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6.4 Å) Cite: Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
8UYE	BtCoV-HKU5 5' proximal stem-loop 5, conformation 1 Descriptor: BtCoV-HKU5 5' proximal stem-loop 5 Authors: Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. Deposit date: 2023-11-13 Release date: 2023-12-06 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
8UYP	SARS-CoV-1 5' proximal stem-loop 5 Descriptor: SARS-CoV-1 5' proximal stem-loop 5 Authors: Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. Deposit date: 2023-11-13 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (7.1 Å) Cite: Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
8UYO	Structure of a recombinant human PNMA2 capsid Descriptor: Paraneoplastic antigen Ma2 Authors: Wilkinson, M.E, Madigan, V, Zhang, Y, Zhang, F. Deposit date: 2023-11-13 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery. Proc.Natl.Acad.Sci.USA, 121, 2024
8X35	Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP, IPP, and magnesium ion (form A) Descriptor: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. Deposit date: 2023-11-12 Release date: 2024-02-07 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
8X37	Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP Descriptor: DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, Neryl-diphosphate synthase 1 Authors: Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. Deposit date: 2023-11-12 Release date: 2024-02-07 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
8X36	Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP, IPP, and magnesium ion (form B) Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, ... Authors: Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. Deposit date: 2023-11-12 Release date: 2024-02-07 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
8R3T	Cofactor-free Tau 4R2N isoform Descriptor: Microtubule-associated protein tau Authors: Limorenko, G, Tatli, M, Kolla, R, Nazarov, S, Weil, M.T, Schondorf, D.C, Geist, D, Reinhardt, P, Ehrnhoefer, D.E, Stahlberg, H, Gasparini, L, Lashuel, H.A. Deposit date: 2023-11-10 Release date: 2023-12-06 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates. Nat Commun, 14, 2023
8R3Z	Cryo-EM structure of the Asgard archaeal Argonaute HrAgo1 bound to a guide RNA Descriptor: HrAgo1, MAGNESIUM ION, RNA (5'-R(P*UP*GP*AP*GP*GP*U*(MG))-3') Authors: Finocchio, G, Swarts, D, Jinek, M. Deposit date: 2023-11-10 Release date: 2024-06-19 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: RNA-guided RNA silencing by an Asgard archaeal Argonaute. Nat Commun, 15, 2024
8R3V	Escherichia coli paused disome complex (non-rotated disome interface) Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ... Authors: Fluegel, T, Schacherl, M. Deposit date: 2023-11-10 Release date: 2024-03-06 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM. Nat Commun, 15, 2024
8R3K	Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide mimic bound in site 1A/2A. Descriptor: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Arragain, B, Cusack, S. Deposit date: 2023-11-09 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.43 Å) Cite: The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8UXL	Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2023-11-09 Release date: 2023-11-22 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXM	Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2023-11-09 Release date: 2023-11-22 Method: ELECTRON MICROSCOPY (3.56 Å) Cite: Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8X22	HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:dGTP ternary complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... Authors: Yasutake, Y, Hattori, S.I, Mitsuya, H. Deposit date: 2023-11-09 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
8X21	HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:ETV-TP ternary complex Descriptor: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... Authors: Yasutake, Y, Hattori, S.I, Mitsuya, H. Deposit date: 2023-11-09 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
8X1Z	HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y:DNA:E-CFCP-TP ternary complex Descriptor: DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... Authors: Yasutake, Y, Hattori, S.I, Mitsuya, H. Deposit date: 2023-11-09 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
8X20	HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:E-CFCP-TP ternary complex Descriptor: DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... Authors: Yasutake, Y, Hattori, S.I, Mitsuya, H. Deposit date: 2023-11-09 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
8X2J	Cryo-EM structure of the photosynthetic alternative complex III with a quinone inhibitor HQNO from Chloroflexus aurantiacus Descriptor: 1,3-bis(13-methyltetradecanoyloxy)propan-2-yl pentadecanoate, 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, Cytochrome c domain-containing protein, ... Authors: Xu, X. Deposit date: 2023-11-09 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo-EM structure of HQNO-bound Alternative Complex III from the anoxygenic phototrophic bacterium Chloroflexus aurantiacus. Plant Cell, 2024
8R3L	Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A Descriptor: 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Arragain, B, Cusack, S. Deposit date: 2023-11-09 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8UX1	Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle Descriptor: 153-bp Widom 601 DNA forward strand, 153-bp Widom 601 DNA reverse strand, GTP-binding nuclear protein Ran, ... Authors: Huang, S.K, Rubinstein, J.L, Kay, L.E. Deposit date: 2023-11-08 Release date: 2023-11-22 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle To Be Published
8UX5	OvsA M401Y/Q430N/A431F from Halomonas utahensis, a hercynine-binding variant with selenoneine-biosynthetic activity Descriptor: FE (III) ION, SODIUM ION, Selenoxide synthase OvsA Authors: Ireland, K.A, Davis, K.M. Deposit date: 2023-11-08 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution Nat.Chem., 2024
8X1V	NMR structure of a bimolecular parallel G-quadruplex formed by AAGGG repeats from pathogenic RFC1 gene Descriptor: DNA (5'-D(*AP*AP*GP*GP*GP*AP*AP*GP*GP*GP*AP*A)-3') Authors: Wang, Y, Guo, P, Han, D. Deposit date: 2023-11-08 Release date: 2024-01-17 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS. Nucleic Acids Res., 52, 2024
8X1H	Crystal structure of N-terminal domain of Nucleocapsid protein of SARS-CoV-2 Descriptor: GLYCEROL, Nucleoprotein Authors: Kumari, S, Gupta, G.D. Deposit date: 2023-11-07 Release date: 2023-11-22 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Unveiling potential inhibitors targeting the nucleocapsid protein of SARS-CoV-2: Structural insights into their binding sites. Int.J.Biol.Macromol., 273, 2024
8UW3	Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state Descriptor: Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... Authors: Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. Deposit date: 2023-11-06 Release date: 2023-12-20 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Template and target-site recognition by human LINE-1 in retrotransposition. Nature, 626, 2024

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