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2AFS
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Crystal structure of the genetic mutant R54W of human glutaminyl cyclase
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
Deposit date:2005-07-26
Release date:2005-08-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2H68
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Descriptor: WD-repeat protein 5
Authors:Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
Deposit date:2006-05-30
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6K
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Descriptor: Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5
Authors:Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H9L
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WDR5delta23
Descriptor: SULFATE ION, WD-repeat protein 5
Authors:Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-06-10
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2AFU
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Crystal structure of human glutaminyl cyclase in complex with glutamine t-butyl ester
Descriptor: Glutaminyl-peptide cyclotransferase, TERT-BUTYL D-ALPHA-GLUTAMINATE, ZINC ION
Authors:Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
Deposit date:2005-07-26
Release date:2005-08-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2H14
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Crystal of WDR5 (apo-form)
Descriptor: WD-repeat protein 5
Authors:Couture, J.F, Collazo, E, Trievel, R.C.
Deposit date:2006-05-15
Release date:2006-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13, 2006
2H6Q
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Descriptor: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
Authors:Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
Deposit date:2006-06-01
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
1ZWB
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STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 2-37, NMR, 10 STRUCTURES
Descriptor: PARATHYROID HORMONE
Authors:Roesch, P, Marx, U.C.
Deposit date:1996-06-17
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure-activity relation of NH2-terminal human parathyroid hormone fragments.
J.Biol.Chem., 273, 1998
1ZWE
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STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 4-37, NMR, 10 STRUCTURES
Descriptor: PARATHYROID HORMONE
Authors:Roesch, P, Marx, U.C.
Deposit date:1996-06-17
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure-activity relation of NH2-terminal human parathyroid hormone fragments.
J.Biol.Chem., 273, 1998
1ZZZ
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Trypsin inhibitors with rigid tripeptidyl aldehydes
Descriptor: 2-{(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}-N-{(2S)-1-[(3R)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl}acetamide, CALCIUM ION, TRYPSIN
Authors:Krishnan, R, Zhang, E, Hakansson, K, Arni, R.K, Tulinsky, A, Lim-Wilby, M.S.L, Levy, O.E, Semple, J.E, Brunck, T.K.
Deposit date:1998-06-02
Release date:1999-06-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
Biochemistry, 37, 1998
2AAK
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UBIQUITIN CONJUGATING ENZYME FROM ARABIDOPSIS THALIANA
Descriptor: UBIQUITIN CONJUGATING ENZYME
Authors:Cook, W.J, Jeffrey, L.C, Sullivan, M.L, Vierstra, R.D.
Deposit date:1997-11-06
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of a ubiquitin-conjugating enzyme (E2).
J.Biol.Chem., 267, 1992
2HL7
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Crystal structure of the periplasmic domain of CcmH from Pseudomonas aeruginosa
Descriptor: Cytochrome C-type biogenesis protein CcmH, TETRAETHYLENE GLYCOL
Authors:Di Matteo, A, Travaglini-Allocatelli, C, Gianni, S, Brunori, M.
Deposit date:2006-07-06
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A strategic protein in cytochrome c maturation: three-dimensional structure of CcmH and binding to apocytochrome c
J.Biol.Chem., 282, 2007
2AX6
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Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With Hydroxyflutamide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE
Authors:Bohl, C.E, Miller, D.D, Chen, J, Bell, C.E, Dalton, J.T.
Deposit date:2005-09-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
J.Biol.Chem., 280, 2005
2AQ5
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Crystal Structure of Murine Coronin-1
Descriptor: Coronin-1A
Authors:Appleton, B.A, Wu, P, Wiesmann, C.
Deposit date:2005-08-17
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes.
Structure, 14, 2006
2AXA
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Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With S-1
Descriptor: Androgen receptor, S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
Authors:Bohl, C.E, Miller, D.D, Chen, J, Bell, C.E, Dalton, J.T.
Deposit date:2005-09-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
J.Biol.Chem., 280, 2005
2AX7
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Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With S-1
Descriptor: Androgen receptor, S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
Authors:Bohl, C.E, Miller, D.D, Chen, J, Bell, C.E, Dalton, J.T.
Deposit date:2005-09-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
J.Biol.Chem., 280, 2005
2B4E
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Crystal Structure of Murine Coronin-1: monoclinic form
Descriptor: Coronin-1A
Authors:Appleton, B.A, Wu, P, Wiesmann, C.
Deposit date:2005-09-23
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes
Structure, 14, 2006
2LML
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Solution NMR structure of holo acyl carrier protein from geobacter Metallireducens refined with nh rdcs, Northeast Structural Genomics consortium target gmr141
Descriptor: 4'-PHOSPHOPANTETHEINE, Putative acyl carrier protein
Authors:Ramelot, T.A, Smola, M.J, Lee, H, Zhao, L, Ciccosanti, C, Foote, E.L, Hamilton, K, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-12-05
Release date:2012-01-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of 4'-phosphopantetheine - GmACP3 from Geobacter metallireducens: a specialized acyl carrier protein with atypical structural features and a putative role in lipopolysaccharide biosynthesis.
Biochemistry, 50, 2011
2J21
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BU of 2j21 by Molmil
Human p53 core domain mutant M133L-V203A-N239Y-N268D-R282W
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Fersht, A.R.
Deposit date:2006-08-15
Release date:2006-09-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
1N31
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BU of 1n31 by Molmil
Structure of A Catalytically Inactive Mutant (K223A) of C-DES with a Substrate (Cystine) Linked to the Co-Factor
Descriptor: CYSTEINE, L-cysteine/cystine lyase C-DES, POTASSIUM ION, ...
Authors:Kaiser, J.T, Bruno, S, Clausen, T, Huber, R, Schiaretti, F, Mozzarelli, A, Kessler, D.
Deposit date:2002-10-25
Release date:2003-01-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Snapshots of the Cystine Lyase "C-DES" during Catalysis: Studies in Solution and in the Crystalline State
J.Biol.Chem., 278, 2003
1OMW
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BU of 1omw by Molmil
Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits
Descriptor: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1
Authors:Lodowski, D.T, Pitcher, J.A, Capel, W.D, Lefkowitz, R.J, Tesmer, J.J.G.
Deposit date:2003-02-26
Release date:2003-06-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma
Science, 300, 2003
2JAF
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Ground state of halorhodopsin T203V
Descriptor: CHLORIDE ION, Halorhodopsin, PALMITIC ACID, ...
Authors:Gmelin, W, Zeth, K, Efremov, R, Heberle, J, Tittor, J, Oesterhelt, D.
Deposit date:2006-11-28
Release date:2006-12-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the L1 intermediate of halorhodopsin at 1.9 angstroms resolution.
Photochem. Photobiol., 83, 2007
2JCC
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AH3 recognition of mutant HLA-A2 W167A
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
Authors:Miller, P, Benhar, Y.P, Biddison, W, Collins, E.J.
Deposit date:2006-12-21
Release date:2007-10-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
J.Mol.Biol., 373, 2007
2JAG
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L1-intermediate of halorhodopsin T203V
Descriptor: CHLORIDE ION, Halorhodopsin, PALMITIC ACID, ...
Authors:Gmelin, W, Zeth, K, Efremov, R, Heberle, J, Tittor, J, Oesterhelt, D.
Deposit date:2006-11-28
Release date:2006-12-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The crystal structure of the L1 intermediate of halorhodopsin at 1.9 angstroms resolution.
Photochem. Photobiol., 83, 2007
1OUN
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CRYSTAL STRUCTURE OF NUCLEAR TRANSPORT FACTOR 2 (NTF2)
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Bullock, T.L, Stewart, M.J.
Deposit date:1996-02-21
Release date:1997-04-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2).
J.Mol.Biol., 260, 1996

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