PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

---

2XS2	Crystal structure of the RRM domain of mouse Deleted in azoospermia-like in complex with RNA, UUGUUCUU Descriptor: 5'-R(*UP*UP*GP*UP*UP*CP*UP*U)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION Authors: Jenkins, H.T, Edwards, T.A. Deposit date: 2010-09-24 Release date: 2011-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL. Proc. Natl. Acad. Sci. U.S.A., 108, 2011
4EWC	Crystal Structure of the Infectious Salmon Anemia Virus Nucleoprotein Descriptor: Putative nucleoprotein Authors: Zheng, W, Tao, Y.J. Deposit date: 2012-04-26 Release date: 2013-05-08 Last modified: 2015-02-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The crystal structure and RNA-binding of an orthomyxovirus nucleoprotein. Plos Pathog., 9, 2013
1QC0	CRYSTAL STRUCTURE OF A 19 BASE PAIR COPY CONTROL RELATED RNA DUPLEX Descriptor: 5'-R(*GP*CP*AP*CP*CP*GP*CP*UP*AP*CP*CP*AP*AP*CP*GP*GP*UP*GP*C)-3', 5'-R(*GP*CP*AP*CP*CP*GP*UP*UP*GP*GP*UP*AP*GP*CP*GP*GP*UP*GP*C)-3', 5'-R(*UP*AP*GP*CP*GP*GP*UP*GP*C)-3', ... Authors: Klosterman, P.S, Shah, S.A, Steitz, T.A. Deposit date: 1999-05-17 Release date: 1999-11-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution. Biochemistry, 38, 1999
1QCU	CRYSTAL STRUCTURE OF AN 18 BASE PAIR COPY CONTROL RELATED RNA DUPLEX Descriptor: 5'-R(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3', AMMONIUM ION Authors: Klosterman, P.S, Shah, S.A, Steitz, T.A. Deposit date: 1999-05-14 Release date: 1999-11-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution. Biochemistry, 38, 1999
3CJ5	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide, RNA-directed RNA polymerase Authors: Hendle, j. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
1NB7	HC-J4 RNA polymerase complexed with short RNA template strand Descriptor: 5'-R(*UP*UP*UP*U)-3', MANGANESE (II) ION, polyprotein Authors: O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. Deposit date: 2002-12-02 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
1DIX	CRYSTAL STRUCTURE OF RNASE LE Descriptor: EXTRACELLULAR RIBONUCLEASE LE Authors: Tanaka, N, Nakamura, K.T. Deposit date: 1999-11-30 Release date: 2000-09-06 Last modified: 2017-10-04 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of a plant ribonuclease, RNase LE. J.Mol.Biol., 298, 2000
5E9W	Crystal structure of mRNA cap guanine-N7 methyltransferase obtained by limited proteolysis Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, mRNA cap guanine-N7 methyltransferase Authors: Petit, P, Cowling, V.H. Deposit date: 2015-10-15 Release date: 2016-07-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.283 Å) Cite: Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM. Nucleic Acids Res., 44, 2016
1EFZ	MUTAGENESIS AND CRYSTALLOGRAPHIC STUDIES OF ZYMOMONAS MOBILIS TRNA-GUANINE TRANSGLYCOSYLASE TO ELUCIDATE THE ROLE OF SERINE 103 FOR ENZYMATIC ACTIVITY Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION Authors: Gradler, U, Ficner, R, Garcia, G.A, Stubbs, M.T, Klebe, G, Reuter, K. Deposit date: 2000-02-11 Release date: 2000-03-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity. FEBS Lett., 454, 1999
6ZWX	Crystal structure of E. coli RNA helicase HrpA Descriptor: ATP-dependent RNA helicase HrpA Authors: Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. Deposit date: 2020-07-29 Release date: 2021-06-30 Last modified: 2021-08-04 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
4Q9Q	Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab Descriptor: (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... Authors: Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. Deposit date: 2014-05-01 Release date: 2014-06-18 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.45 Å) Cite: A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
1OS5	Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor. Descriptor: 3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE, Hepatitis C virus NS5B RNA polymerase Authors: Love, R.A, Parge, H.E, Yu, X, Hickey, M.J, Diehl, W, Gao, J, Wriggers, H, Ekker, A, Wang, L, Thomson, J.A, Dragovich, P.S, Fuhrman, S.A. Deposit date: 2003-03-18 Release date: 2004-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme. J.Virol., 77, 2003
3Q22	X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GTP and Magnesium: substrate complex I Descriptor: DIHYDROGENPHOSPHATE ION, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Gleghorn, M.L, Murakami, K.S. Deposit date: 2010-12-19 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.11 Å) Cite: X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108, 2011
8UO1	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
6V9D	Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin Descriptor: 2-[(E)-(1-methylquinolin-4(1H)-ylidene)methyl]-3-(2-oxopropyl)-1,3-benzothiazol-3-ium, BROMIDE ION, POTASSIUM ION, ... Authors: Trachman, R.J, Ferre-D'Amare, A.R. Deposit date: 2019-12-13 Release date: 2020-05-20 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair. Structure, 28, 2020
6V9B	Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin Descriptor: POTASSIUM ION, RNA (28-MER), ~{N}-methyl-2-[2-[(~{E})-(1-methylquinolin-4-ylidene)methyl]-1,3-benzothiazol-3-yl]ethanamide Authors: Trachman, R.J, Ferre-D'Amare, A.R. Deposit date: 2019-12-13 Release date: 2020-05-20 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair. Structure, 28, 2020
3IVK	Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment Descriptor: CADMIUM ION, CHLORIDE ION, Fab heavy chain, ... Authors: Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A. Deposit date: 2009-09-01 Release date: 2010-03-02 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
8GAP	Structure of LARP7 protein p65-telomerase RNA complex in telomerase Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... Authors: Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J. Deposit date: 2023-02-23 Release date: 2023-06-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR. J.Mol.Biol., 435, 2023
4QU6	Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 1.75 A resolution Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2014-07-10 Release date: 2014-08-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 1.75 A resolution To be published
7DMQ	Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex Descriptor: Anti-tag target RNA, CRISPR RNA, CRISPR/Cas system Cas13a Authors: Wang, B, Zhang, T, Ding, J, Patel, D.J, Yang, H. Deposit date: 2020-12-05 Release date: 2021-02-10 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems. Mol.Cell, 81, 2021
483D	CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA Descriptor: SARCIN/RICIN RRNA DOMAIN Authors: Correll, C.C, Wool, I.G, Munishkin, A. Deposit date: 1999-07-23 Release date: 1999-10-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.11 Å) Cite: The two faces of the Escherichia coli 23 S rRNA sarcin/ricin domain: the structure at 1.11 A resolution. J.Mol.Biol., 292, 1999
2B9Z	Solution structure of FHV B2, a viral suppressor of RNAi Descriptor: B2 protein Authors: Lingel, A, Simon, B, Izaurralde, E, Sattler, M. Deposit date: 2005-10-13 Release date: 2005-11-29 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. Embo Rep., 6, 2005
3N6M	Crystal structure of EV71 RdRp in complex with GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase Authors: Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H. Deposit date: 2010-05-26 Release date: 2011-06-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1, 2010
480D	CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA Descriptor: SARCIN/RICIN DOMAIN FROM 23 S RRNA Authors: Correll, C.C, Wool, I.G, Munishkin, A. Deposit date: 1999-07-20 Release date: 1999-10-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The two faces of the Escherichia coli 23 S rRNA sarcin/ricin domain: the structure at 1.11 A resolution. J.Mol.Biol., 292, 1999
3Q23	X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II Descriptor: DIHYDROGENPHOSPHATE ION, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), MANGANESE (II) ION, ... Authors: Gleghorn, M.L, Murakami, K.S. Deposit date: 2010-12-19 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108, 2011

<300301302303304305306307308309310311312313314315>