6V9D

Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin

Summary for 6V9D

• Entry DOI: 10.2210/pdb6v9d/pdb
• Related: 6V9B
• Descriptor: RNA (28-MER), 2-[(E)-(1-methylquinolin-4(1H)-ylidene)methyl]-3-(2-oxopropyl)-1,3-benzothiazol-3-ium, BROMIDE ION, ... (4 entities in total)
• Functional Keywords: rna, aptamer, fluorescence
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 19825.68

Authors

Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2019-12-13, release date: 2020-05-20, Last modification date: 2024-03-06)

• Primary citation: Trachman 3rd, R.J.,Cojocaru, R.,Wu, D.,Piszczek, G.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R.; Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.; Structure, 28:776-785.e3, 2020; PubMed: 32386573; DOI: 10.1016/j.str.2020.04.007

Experimental method

X-RAY DIFFRACTION (2.8 Å)