6V9B
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
Summary for 6V9B
Entry DOI | 10.2210/pdb6v9b/pdb |
Descriptor | RNA (28-MER), ~{N}-methyl-2-[2-[(~{E})-(1-methylquinolin-4-ylidene)methyl]-1,3-benzothiazol-3-yl]ethanamide, POTASSIUM ION (3 entities in total) |
Functional Keywords | rna, aptamer, fluorescence |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 19710.91 |
Authors | Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2019-12-13, release date: 2020-05-20, Last modification date: 2024-03-06) |
Primary citation | Trachman 3rd, R.J.,Cojocaru, R.,Wu, D.,Piszczek, G.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R. Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair. Structure, 28:776-785.e3, 2020 Cited by PubMed: 32386573DOI: 10.1016/j.str.2020.04.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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