1P3O
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![BU of 1p3o by Molmil](/molmil-images/mine/1p3o) | Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants | Descriptor: | Histone H2A, Histone H2B, Histone H3, ... | Authors: | Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. | Deposit date: | 2003-04-17 | Release date: | 2004-02-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
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1TBD
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![BU of 1tbd by Molmil](/molmil-images/mine/1tbd) | SOLUTION STRUCTURE OF THE ORIGIN DNA BINDING DOMAIN OF SV40 T-ANTIGEN, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | SV40 T-ANTIGEN | Authors: | Luo, X, Sanford, D.G, Bullock, P.A, Bachovchin, W.W. | Deposit date: | 1996-11-04 | Release date: | 1997-03-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat.Struct.Biol., 3, 1996
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3H8O
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![BU of 3h8o by Molmil](/molmil-images/mine/3h8o) | Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system | Descriptor: | 5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*(MA7)P*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*TP*AP*TP*AP*AP*TP*AP*CP*A)-3', Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ... | Authors: | Lu, L, Yi, C, Jian, X, Zheng, Q. | Deposit date: | 2009-04-29 | Release date: | 2010-03-31 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res., 38, 2010
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2EZK
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![BU of 2ezk by Molmil](/molmil-images/mine/2ezk) | SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, REGULARIZED MEAN STRUCTURE | Descriptor: | TRANSPOSASE | Authors: | Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M. | Deposit date: | 1997-10-04 | Release date: | 1998-01-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains. EMBO J., 16, 1997
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1NH3
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![BU of 1nh3 by Molmil](/molmil-images/mine/1nh3) | Human Topoisomerase I Ara-C Complex | Descriptor: | 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... | Authors: | Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. | Deposit date: | 2002-12-18 | Release date: | 2003-03-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex J.Biol.Chem., 278, 2003
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6S1C
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![BU of 6s1c by Molmil](/molmil-images/mine/6s1c) | P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex | Descriptor: | Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... | Authors: | Grabarczyk, D.B. | Deposit date: | 2019-06-18 | Release date: | 2020-07-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (6.1 Å) | Cite: | Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
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6OZJ
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6OZQ
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![BU of 6ozq by Molmil](/molmil-images/mine/6ozq) | |
6OZP
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1F2I
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![BU of 1f2i by Molmil](/molmil-images/mine/1f2i) | COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA | Descriptor: | 5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3', FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, ZINC ION | Authors: | Wang, B.S, Grant, R.A, Pabo, C.O. | Deposit date: | 2000-05-25 | Release date: | 2001-09-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nat.Struct.Biol., 8, 2001
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6OZS
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4HLX
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![BU of 4hlx by Molmil](/molmil-images/mine/4hlx) | |
6VDK
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![BU of 6vdk by Molmil](/molmil-images/mine/6vdk) | CryoEM structure of HIV-1 conserved Intasome Core | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | Authors: | Li, M, Chen, X, Craigie, R. | Deposit date: | 2019-12-27 | Release date: | 2020-02-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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6OZK
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6VBW
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![BU of 6vbw by Molmil](/molmil-images/mine/6vbw) | |
6OZR
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![BU of 6ozr by Molmil](/molmil-images/mine/6ozr) | |
6OZM
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![BU of 6ozm by Molmil](/molmil-images/mine/6ozm) | |
6OZO
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![BU of 6ozo by Molmil](/molmil-images/mine/6ozo) | |
4BHM
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![BU of 4bhm by Molmil](/molmil-images/mine/4bhm) | The crystal structure of MoSub1-DNA complex reveals a novel DNA binding mode | Descriptor: | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP)-3', MOSUB1 TRANSCRIPTION COFACTOR, SULFATE ION | Authors: | Huang, J, Liu, H, Zhao, Y, Huang, D, liu, J, Peng, Y. | Deposit date: | 2013-04-04 | Release date: | 2014-04-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4. Sci.Rep., 5, 2015
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4PY5
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![BU of 4py5 by Molmil](/molmil-images/mine/4py5) | Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA | Descriptor: | 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', GLYCEROL, ... | Authors: | Figiel, M, Nowotny, M. | Deposit date: | 2014-03-26 | Release date: | 2014-07-30 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition. Nucleic Acids Res., 42, 2014
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6OZN
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5U9D
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![BU of 5u9d by Molmil](/molmil-images/mine/5u9d) | Discovery of a potent BTK inhibitor with a novel binding mode using parallel selections with a DNA-encoded chemical library | Descriptor: | (R)-N-methyl-2-(3-((quinoxalin-6-ylamino)methyl)furan-2-carbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Cuozzo, J.W, Centrella, P.A, Gikunju, D, Habeshian, S, Hupp, C.D, Keefe, A.D, Sigel, E, Soutter, H.H, Thomson, H.A, Zhang, Y, Clark, M.A. | Deposit date: | 2016-12-16 | Release date: | 2017-01-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library. Chembiochem, 18, 2017
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7BSE
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7BSF
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3IH7
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![BU of 3ih7 by Molmil](/molmil-images/mine/3ih7) | |