7LI7
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7LI6
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![BU of 7li6 by Molmil](/molmil-images/mine/7li6) | apo SERT reconstituted in lipid nanodisc in KCl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Yang, D, Gouaux, E. | Deposit date: | 2021-01-26 | Release date: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Illumination of serotonin transporter mechanism and role of the allosteric site. Sci Adv, 7, 2021
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6TCQ
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![BU of 6tcq by Molmil](/molmil-images/mine/6tcq) | Crystal structure of the omalizumab Fab Ser81Arg and Gln83Arg light chain mutant | Descriptor: | GLYCEROL, Omalizumab Fab Ser81Arg and Gln83Arg light chain mutant | Authors: | Mitropoulou, A.N, Ceska, T, Beavil, A.J, Henry, A.J, McDonnell, J.M, Sutton, B.J, Davies, A.M. | Deposit date: | 2019-11-06 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization. Acta Crystallogr.,Sect.F, 76, 2020
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2OCW
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6SUZ
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6SV2
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6TCN
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![BU of 6tcn by Molmil](/molmil-images/mine/6tcn) | Crystal structure of the omalizumab Fab - crystal form II | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mitropoulou, A.N, Ceska, T, Beavil, A.J, Henry, A.J, McDonnell, J.M, Sutton, B.J, Davies, A.M. | Deposit date: | 2019-11-06 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization. Acta Crystallogr.,Sect.F, 76, 2020
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2BE2
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![BU of 2be2 by Molmil](/molmil-images/mine/2be2) | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239 | Descriptor: | 4-(3,5-DIMETHYLPHENOXY)-5-(FURAN-2-YLMETHYLSULFANYLMETHYL)-3-IODO-6-METHYLPYRIDIN-2(1H)-ONE, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Himmel, D.M, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Nguyen, C.H, Grierson, D.S, Arnold, E. | Deposit date: | 2005-10-21 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
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7L8P
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![BU of 7l8p by Molmil](/molmil-images/mine/7l8p) | Integrin alphaIIbbeta3 in complex with sibrafiban | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lin, F.-Y, Springer, T.A. | Deposit date: | 2020-12-31 | Release date: | 2022-06-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.34995365 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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2B5J
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![BU of 2b5j by Molmil](/molmil-images/mine/2b5j) | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481 | Descriptor: | (2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE, MANGANESE (II) ION, Reverse transcriptase P51 SUBUNIT, ... | Authors: | Himmel, D.H, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Mguyen, C.H, Grierson, D.S, Arnold, E. | Deposit date: | 2005-09-28 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
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2BAN
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![BU of 2ban by Molmil](/molmil-images/mine/2ban) | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R157208 | Descriptor: | 5-ETHYL-3-[(2-METHOXYETHYL)METHYLAMINO]-6-METHYL-4-(3-METHYLBENZYL)PYRIDIN-2(1H)-ONE, MANGANESE (II) ION, Reverse transcriptase P51 subunit, ... | Authors: | Das, K, Arnold, E. | Deposit date: | 2005-10-14 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
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7KGV
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![BU of 7kgv by Molmil](/molmil-images/mine/7kgv) | Crystal structure of sodium-coupled neutral amino acid transporter SLC38A9 in the N-terminal plugged form | Descriptor: | Monoclonal antibody Fab heavy chain, Monoclonal antibody Fab light chain, Sodium-coupled neutral amino acid transporter 9 | Authors: | Lei, H, Mu, X, Hattne, J, Gonen, T. | Deposit date: | 2020-10-19 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | A conformational change in the N terminus of SLC38A9 signals mTORC1 activation. Structure, 29, 2021
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7M2J
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7M2I
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7M7E
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![BU of 7m7e by Molmil](/molmil-images/mine/7m7e) | 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7H
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![BU of 7m7h by Molmil](/molmil-images/mine/7m7h) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7J
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![BU of 7m7j by Molmil](/molmil-images/mine/7m7j) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7G
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![BU of 7m7g by Molmil](/molmil-images/mine/7m7g) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7I
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![BU of 7m7i by Molmil](/molmil-images/mine/7m7i) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7F
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![BU of 7m7f by Molmil](/molmil-images/mine/7m7f) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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2ESX
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![BU of 2esx by Molmil](/molmil-images/mine/2esx) | The structure of the V3 region within gp120 of JR-FL HIV-1 strain (minimized average structure) | Descriptor: | Envelope polyprotein GP160 | Authors: | Rosen, O, Sharon, M, Samson, A.O, Quadt, S.R, Anglister, J. | Deposit date: | 2005-10-27 | Release date: | 2006-09-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular switch for alternative conformations of the HIV-1 V3 region: Implications for phenotype conversion. Proc.Natl.Acad.Sci.Usa, 13, 2006
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2ESZ
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![BU of 2esz by Molmil](/molmil-images/mine/2esz) | The structure of the V3 region within gp120 of JR-FL HIV-1 strain (ensemble) | Descriptor: | Envelope polyprotein GP160 | Authors: | Rosen, O, Sharon, M, Samson, A.O, Quadt, S.R, Anglister, J. | Deposit date: | 2005-10-27 | Release date: | 2006-09-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular switch for alternative conformations of the HIV-1 V3 region: Implications for phenotype conversion. Proc.Natl.Acad.Sci.Usa, 13, 2006
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1MVF
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![BU of 1mvf by Molmil](/molmil-images/mine/1mvf) | MazE addiction antidote | Descriptor: | PemI-like protein 1, immunoglobulin heavy chain variable region | Authors: | Loris, R, Marianovsky, I, Lah, J, Laeremans, T, Engelberg-Kulka, H, Glaser, G, Muyldermans, S, Wyns, L. | Deposit date: | 2002-09-25 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the intrinsically flexible addiction antidote MazE. J.Biol.Chem., 278, 2003
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1OAK
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5VKD
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![BU of 5vkd by Molmil](/molmil-images/mine/5vkd) | Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab light chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | Deposit date: | 2017-04-21 | Release date: | 2018-04-25 | Last modified: | 2022-11-16 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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