PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

---

7SN8	Cryo-EM structure of Drosophila Integrator cleavage module (IntS4-IntS9-IntS11) in complex with IP6 Descriptor: INOSITOL HEXAKISPHOSPHATE, Integrator complex subunit 11, Integrator complex subunit 4, ... Authors: Lin, M, Tong, L. Deposit date: 2021-10-27 Release date: 2022-10-12 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.74 Å) Cite: Inositol hexakisphosphate is required for Integrator function. Nat Commun, 13, 2022
8OR4	Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2 Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, Cyclin-dependent kinase 2, ... Authors: Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I. Deposit date: 2023-04-13 Release date: 2023-06-28 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange. Mol.Cell, 83, 2023
4M4Q	6-(4-fluorophenyl)-3-hydroxy-5-[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl] -1,2-dihydropyridin-2-one bound to influenza 2009 H1N1 endonuclease Descriptor: 6-(4-fluorophenyl)-5-[4-(1H-tetrazol-5-yl)phenyl]pyridine-2,3-diol, MAGNESIUM ION, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-07 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5Q	High-resolution apo influenza 2009 H1N1 endonuclease structure Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Polymerase PA Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.534 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5R	High-resolution influenza 2009 H1N1 endonuclease bound to 4-(1H-IMIDAZOL-1-YL)PHENOL Descriptor: 1,2-ETHANEDIOL, 4-(1H-IMIDAZOL-1-YL)PHENOL, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5O	3-HYDROXY-6-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 H1N1 endonuclease Descriptor: 1,2-ETHANEDIOL, 3-hydroxy-6-phenylpyridin-2(5H)-one, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
5O8K	Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B Authors: Emamzadah, S, Tropia, L, Huber, F, Halazonetis, T. Deposit date: 2017-06-13 Release date: 2018-06-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 To Be Published
4E6A	p38a-PIA23 complex Descriptor: (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14 Authors: Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. Deposit date: 2012-03-15 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch. J.Mol.Biol., 424, 2012
2WHX	A second conformation of the NS3 protease-helicase from dengue virus Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MANGANESE (II) ION, ... Authors: Luo, D, Lescar, J. Deposit date: 2009-05-07 Release date: 2010-04-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications. J.Biol.Chem., 285, 2010
4E5A	The W197A mutant of p38a MAP kinase Descriptor: Mitogen-activated protein kinase 14 Authors: Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. Deposit date: 2012-03-14 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch. J.Mol.Biol., 424, 2012
4JGH	Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5 Descriptor: Cullin-5, Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, ... Authors: Kim, Y.K, Kwak, M.J, Ku, B, Suh, H.Y, Joo, K, Lee, J, Jung, J.U, Oh, B.H. Deposit date: 2013-03-01 Release date: 2013-08-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes. Acta Crystallogr.,Sect.D, 69, 2013
4M5V	Influenza 2009 H1N1 endonuclease with 100 millimolar calcium Descriptor: CALCIUM ION, Polymerase PA, SULFATE ION Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
2ZU6	crystal structure of the eIF4A-PDCD4 complex Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... Authors: Cho, Y, Chang, J.H, Sohn, S.Y. Deposit date: 2008-10-13 Release date: 2009-02-24 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of the eIF4A-PDCD4 complex Proc.Natl.Acad.Sci.Usa, 106, 2009
5VFR	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... Authors: Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. Deposit date: 2017-04-09 Release date: 2018-07-18 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
5VFQ	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... Authors: Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. Deposit date: 2017-04-09 Release date: 2018-07-18 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
3GQE	Crystal structure of macro domain of Venezuelan Equine Encephalitis virus Descriptor: BICINE, Non-structural protein 3 Authors: Jamal, S, Malet, H, Coutard, B, Canard, B. Deposit date: 2009-03-24 Release date: 2009-07-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
6ERO	Structure of human TFB2M Descriptor: CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ... Authors: Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. Deposit date: 2017-10-18 Release date: 2017-11-15 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural Basis of Mitochondrial Transcription Initiation. Cell, 171, 2017
4XZC	The crystal structure of Kupe virus nucleoprotein Descriptor: Nucleoprotein Authors: Guo, Y, Wang, W, Liu, X, Wang, X, Wang, J, Huo, T, Liu, B. Deposit date: 2015-02-04 Release date: 2015-09-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins. J.Virol., 89, 2015
4XZA	The crystal structure of Erve virus nucleoprotein Descriptor: Nucleoprotein Authors: Guo, Y, Wang, W, Liu, X, Wang, X, Wang, J, Huo, T, Liu, B. Deposit date: 2015-02-04 Release date: 2015-09-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins. J.Virol., 89, 2015
4XZ8	The crystal structure of Erve virus nucleoprotein Descriptor: Nucleoprotein Authors: Guo, Y, Wang, W, Liu, X, Wang, X, Wang, J, Huo, T, Liu, B. Deposit date: 2015-02-04 Release date: 2015-09-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins. J.Virol., 89, 2015
2JR0	Solution structure of NusB from Aquifex Aeolicus Descriptor: N utilization substance protein B homolog Authors: Das, R, Loss, S, Li, J, Tarasov, S, Wingfield, P, Waugh, D.S, Byrd, R.A, Altieri, A.S. Deposit date: 2007-06-18 Release date: 2008-02-19 Last modified: 2024-05-08 Method: SOLUTION NMR Cite: Structural biophysics of the NusB:NusE antitermination complex. J.Mol.Biol., 376, 2008
5VFP	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... Authors: Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. Deposit date: 2017-04-09 Release date: 2018-07-18 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
5VFS	Nucleotide-Driven Triple-State Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... Authors: Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. Deposit date: 2017-04-09 Release date: 2018-07-18 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
7S4E	Crystal Structure of ligand ACBi1 in complex with bromodomain of human Smarca2 and pVHL:ElonginC:ElonginB complex Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Elongin-B, ... Authors: MacPherson, D.J, Sherman, W. Deposit date: 2021-09-08 Release date: 2022-10-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry. Nat Commun, 13, 2022
3GPO	Crystal structure of macro domain of Chikungunya virus in complex with ADP-ribose Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 Authors: Malet, H, Jamal, S, Coutard, B, Canard, B. Deposit date: 2009-03-23 Release date: 2009-07-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009

<245246247248249250251252253254255256257258259260>