5VFS

Nucleotide-Driven Triple-State Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome

This is a non-PDB format compatible entry.

Summary for 5VFS

• Entry DOI: 10.2210/pdb5vfs/pdb
• Related: 5VFO 5VFP 5VFQ 5VFR 5VFT 5VFU
• EMDB information: 8662 8663 8664 8665 8666 8667 8668
• Descriptor: Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (34 entities in total)
• Functional Keywords: 26s proteasome, atp-dependent protease, aaa-atpase, peptide-unfolding channel, 20s core particle, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 46
• Total formula weight: 1532632.25

Authors

Zhu, Y.,Wang, W.L.,Yu, D.,Ouyang, Q.,Lu, Y.,Mao, Y. (deposition date: 2017-04-09, release date: 2018-07-18)

• Primary citation: Zhu, Y.,Wang, W.L.,Yu, D.,Ouyang, Q.,Lu, Y.,Mao, Y.; Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.; Nat Commun, 9:1360-1360, 2018; PubMed: 29636472; DOI: 10.1038/s41467-018-03785-w

Experimental method

ELECTRON MICROSCOPY (3.6 Å)