Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4E6A

p38a-PIA23 complex

Summary for 4E6A
Entry DOI10.2210/pdb4e6a/pdb
Related1P38 2NPQ 4E5A 4E5B 4E6C 4E8A
DescriptorMitogen-activated protein kinase 14, (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate (3 entities in total)
Functional Keywordsmap kinase, p38, signal transduction, alternative activation modes, lipid binding site, pia, perifosine, kinase fold, kinase, substrates, phosphorylation, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : Q16539
Total number of polymer chains1
Total formula weight41984.02
Authors
Livnah, O.,Tzarum, N.,Eisenberg-Domovich, Y. (deposition date: 2012-03-15, release date: 2012-10-31, Last modification date: 2024-02-28)
Primary citationTzarum, N.,Eisenberg-Domovich, Y.,Gills, J.J.,Dennis, P.A.,Livnah, O.
Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424:339-353, 2012
Cited by
PubMed: 23079240
DOI: 10.1016/j.jmb.2012.10.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.09 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon