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2C62
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BU of 2c62 by Molmil
Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15, SULFATE ION
Authors:Werten, S, Moras, D.
Deposit date:2005-11-07
Release date:2006-01-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A Global Transcription Cofactor Bound to Juxtaposed Strands of Unwound DNA
Nat.Struct.Mol.Biol., 13, 2006
5XE7
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BU of 5xe7 by Molmil
Crystal structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigJ
Descriptor: ECF RNA polymerase sigma factor SigJ
Authors:Goutam, K, Gopal, B.
Deposit date:2017-04-01
Release date:2017-07-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:The fused SnoaL_2 domain in the Mycobacterium tuberculosis sigma factor sigma J modulates promoter recognition
Nucleic Acids Res., 45, 2017
6YWN
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BU of 6ywn by Molmil
CutA in complex with CMPCPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CALCIUM ION, CutA
Authors:Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M.
Deposit date:2020-04-29
Release date:2020-08-05
Last modified:2020-09-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
6NZ2
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BU of 6nz2 by Molmil
NMR solution structure of Bcd1p120-303 from Saccharomyces cerevisiae
Descriptor: Box C/D snoRNA protein 1
Authors:Bragantini, B, Quinternet, M, Charpentier, B, Manival, X.
Deposit date:2019-02-12
Release date:2020-08-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity.
Nat Commun, 12, 2021
6YWP
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BU of 6ywp by Molmil
Structure of apo-CutA
Descriptor: CutA, MAGNESIUM ION
Authors:Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M.
Deposit date:2020-04-29
Release date:2020-08-05
Last modified:2020-09-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7M09
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BU of 7m09 by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with blunt-ended DSB substrate and incoming dUMPNPP
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ...
Authors:Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
Deposit date:2021-03-10
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
7M0D
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BU of 7m0d by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound complementary DSB substrate and incoming dUMPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
Deposit date:2021-03-10
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
7M0B
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BU of 7m0b by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound mismatched DSB and incoming dUMPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
Deposit date:2021-03-10
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
7M07
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BU of 7m07 by Molmil
Pre-catalytic ternary complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
Deposit date:2021-03-10
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
Descriptor: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6XEO
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BU of 6xeo by Molmil
Structure of Mfd bound to dsDNA
Descriptor: DNA (5'-D(P*AP*GP*GP*AP*TP*AP*CP*TP*TP*AP*CP*AP*GP*CP*CP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*GP*GP*CP*TP*GP*TP*AP*AP*GP*TP*AP*TP*CP*CP*T)-3'), Transcription-repair-coupling factor
Authors:Brugger, C, Deaconescu, A.
Deposit date:2020-06-12
Release date:2020-08-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd.
Nat Commun, 11, 2020
4P9A
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BU of 4p9a by Molmil
X-ray Crystal Structure of PA protein from Influenza strain H7N9
Descriptor: GLYCEROL, Polymerase PA
Authors:Fairman, J.W, Moen, S.O, Clifton, M.C, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-02
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1999 Å)
Cite:Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Sci Rep, 4, 2014
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
Deposit date:2017-11-01
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2HHX
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BU of 2hhx by Molmil
O6-methyl-guanine in the polymerase template preinsertion site
Descriptor: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', DNA Polymerase I, ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6FS6
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BU of 6fs6 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
2HHU
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BU of 2hhu by Molmil
C:O6-methyl-guanine in the polymerase postinsertion site (-1 basepair position)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*CP*C)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*GP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', ...
Authors:Warren, J.J, Forsberg, L.J, Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6FS7
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BU of 6fs7 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
4OR6
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BU of 4or6 by Molmil
Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
Authors:Liu, Y, Fan, J, Zheng, X.
Deposit date:2014-02-11
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015
2IQH
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BU of 2iqh by Molmil
Influenza A virus nucleoprotein NP at 3.2A resolution
Descriptor: Nucleocapsid protein
Authors:Ye, Q, Tao, Y.J.
Deposit date:2006-10-13
Release date:2006-12-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA.
Nature, 444, 2006
4Q46
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BU of 4q46 by Molmil
The second structure of Influenza B PB2 cap-binding domain complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
Authors:Liu, Y, Yang, Y, Zheng, X.
Deposit date:2014-04-13
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015
6Z3U
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BU of 6z3u by Molmil
Structure of the CAK complex form Chaetomium thermophilum
Descriptor: CHLORIDE ION, CYCLIN domain-containing protein, Protein kinase domain-containing protein, ...
Authors:Peissert, S, Kuper, J, Kisker, C.
Deposit date:2020-05-22
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for CDK7 activation by MAT1 and Cyclin H.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PFJ
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BU of 6pfj by Molmil
Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor
Authors:Schumacher, M.A.
Deposit date:2019-06-21
Release date:2019-11-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
6USR
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BU of 6usr by Molmil
Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp
Descriptor: DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ...
Authors:Schaich, M.A, Freudenthal, B.D.
Deposit date:2019-10-28
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Mechanisms of nucleotide selection by telomerase.
Elife, 9, 2020
6ONO
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BU of 6ono by Molmil
Complex structure of WhiB1 and region 4 of SigA in C2221 space group
Descriptor: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
Authors:Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
Deposit date:2019-04-22
Release date:2019-11-27
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020

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