6VWY
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6Z8P
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![BU of 6z8p by Molmil](/molmil-images/mine/6z8p) | C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH GSK973 | Descriptor: | (2~{S},3~{S})-2-(fluoranylmethyl)-~{N}7-methyl-~{N}5-[(1~{R},5~{S})-3-oxabicyclo[3.1.0]hexan-6-yl]-3-phenyl-2,3-dihydro-1-benzofuran-5,7-dicarboxamide, 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... | Authors: | Chung, C. | Deposit date: | 2020-06-02 | Release date: | 2020-10-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family. Acs Med.Chem.Lett., 11, 2020
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1H8G
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![BU of 1h8g by Molmil](/molmil-images/mine/1h8g) | C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | Descriptor: | CHOLINE ION, MAJOR AUTOLYSIN | Authors: | Fernandez-Tornero, C, Garcia, E, Lopez, R, Gimenez-Gallego, G, Romero, A. | Deposit date: | 2001-02-06 | Release date: | 2002-01-31 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta Nat.Struct.Biol., 8, 2001
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7STA
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8TLM
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![BU of 8tlm by Molmil](/molmil-images/mine/8tlm) | Structure of a class A GPCR/Fab complex | Descriptor: | C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ... | Authors: | Sun, D, Johnson, M, Masureel, M. | Deposit date: | 2023-07-27 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14, 2023
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7SCU
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![BU of 7scu by Molmil](/molmil-images/mine/7scu) | Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7 | Descriptor: | C-C motif chemokine 7, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2021-09-29 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure of Tick Evasin EVA-AAM1001 complexed to human chemokine CCL7 To Be Published
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7SO0
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![BU of 7so0 by Molmil](/molmil-images/mine/7so0) | Crystal Structure of the Engineered Tick Evasin EVA-P974(F31A) Complexed to Human Chemokine CCL2 | Descriptor: | C-C motif chemokine 2, Evasin P974 | Authors: | Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2021-10-28 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases. Proc.Natl.Acad.Sci.USA, 119, 2022
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8QB1
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![BU of 8qb1 by Molmil](/molmil-images/mine/8qb1) | C-terminal domain of mirolase from Tannerella forsythia | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Mirolase, ... | Authors: | Gomis-Ruth, F.X, Rodriguez-Banqueri, A, Mizgalska, D, Veillard, F, Goulas, T, Eckhard, U, Potempa, J. | Deposit date: | 2023-08-23 | Release date: | 2024-02-28 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Structural and functional insights into the C-terminal signal domain of the Bacteroidetes type-IX secretion system. Open Biology, 14, 2024
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5LWE
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![BU of 5lwe by Molmil](/molmil-images/mine/5lwe) | Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon | Descriptor: | C-C chemokine receptor type 9, CHOLESTEROL, MALONATE ION, ... | Authors: | Oswald, C, Rappas, M, Kean, J, Dore, A.S, Errey, J.C, Bennett, K, Deflorian, F, Christopher, J.A, Jazayeri, A, Mason, J.S, Congreve, M, Cooke, R.M, Marshall, F.H. | Deposit date: | 2016-09-16 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Intracellular allosteric antagonism of the CCR9 receptor. Nature, 540, 2016
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7BVR
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![BU of 7bvr by Molmil](/molmil-images/mine/7bvr) | DgpB-DgpC complex apo | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AP_endonuc_2 domain-containing protein, DgpB, ... | Authors: | Mori, T, He, H, Abe, I. | Deposit date: | 2020-04-11 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes. Nat Commun, 12, 2021
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6Z7F
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4RWS
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![BU of 4rws by Molmil](/molmil-images/mine/4rws) | Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target) | Descriptor: | C-X-C chemokine receptor type 4/Endolysin chimeric protein, Viral macrophage inflammatory protein 2 | Authors: | Qin, L, Kufareva, I, Holden, L, Wang, C, Zheng, Y, Wu, H, Fenalti, G, Han, G.W, Cherezov, V, Abagyan, R, Stevens, R.C, Handel, T.M, GPCR Network (GPCR) | Deposit date: | 2014-12-05 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science, 347, 2015
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6GPS
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![BU of 6gps by Molmil](/molmil-images/mine/6gps) | CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812 | Descriptor: | C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2, ZINC ION, [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium | Authors: | Pautsch, A, Schnapp, G. | Deposit date: | 2018-06-07 | Release date: | 2019-01-02 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists. Structure, 27, 2019
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7CYW
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6M75
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![BU of 6m75 by Molmil](/molmil-images/mine/6m75) | C-Myc DNA binding protein complex | Descriptor: | DNA (5'-D(*TP*CP*TP*TP*AP*TP*T)-3'), RNA-binding motif, single-stranded-interacting protein 1, ... | Authors: | Aggarwal, P, Bhavesh, N.S. | Deposit date: | 2020-03-17 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter. Nucleic Acids Res., 49, 2021
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8SKK
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![BU of 8skk by Molmil](/molmil-images/mine/8skk) | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL17 | Descriptor: | C-C motif chemokine 17, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2023-04-19 | Release date: | 2023-05-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7 To be Published
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7U6V
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![BU of 7u6v by Molmil](/molmil-images/mine/7u6v) | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk | Descriptor: | C-terminal domain (CTD) from the Ribosomal P-stalk, Shiga toxin 2a subunit A (Stx2A), Shiga toxin 2a subunit B (Stx2B) | Authors: | Kulczyk, A.W. | Deposit date: | 2022-03-06 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. J.Biol.Chem., 299, 2022
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7TSJ
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8FWA
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![BU of 8fwa by Molmil](/molmil-images/mine/8fwa) | Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography | Descriptor: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ... | Authors: | Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A. | Deposit date: | 2023-01-20 | Release date: | 2023-06-28 | Last modified: | 2023-07-12 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme. Lab Chip, 23, 2023
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6GPX
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![BU of 6gpx by Molmil](/molmil-images/mine/6gpx) | CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812 | Descriptor: | C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2, OLEIC ACID, ZINC ION, ... | Authors: | Pautsch, A, Schnapp, G, Cheng, R, Apel, A. | Deposit date: | 2018-06-07 | Release date: | 2019-01-02 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists. Structure, 27, 2019
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7BVS
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![BU of 7bvs by Molmil](/molmil-images/mine/7bvs) | DfgA-DfgB complex apo | Descriptor: | DfgB, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Mori, T, He, H, Abe, I. | Deposit date: | 2020-04-11 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes. Nat Commun, 12, 2021
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6F1S
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![BU of 6f1s by Molmil](/molmil-images/mine/6f1s) | C-terminal domain of CglI restriction endonuclease H subunit | Descriptor: | 1,2-ETHANEDIOL, CglIIR protein, FORMIC ACID | Authors: | Tamulaitiene, G, Grigaitis, R, Zaremba, M, Silanskas, A. | Deposit date: | 2017-11-23 | Release date: | 2018-02-14 | Last modified: | 2019-01-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor. Nucleic Acids Res., 46, 2018
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7EXZ
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![BU of 7exz by Molmil](/molmil-images/mine/7exz) | DgpB-DgpC complex apo 2.5 angstrom | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AP_endonuc_2 domain-containing protein, DgpB, ... | Authors: | Mori, T, Senda, M, Senda, T, Abe, I. | Deposit date: | 2021-05-29 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes. Nat Commun, 12, 2021
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6EY6
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4R8I
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![BU of 4r8i by Molmil](/molmil-images/mine/4r8i) | High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2 | Descriptor: | C-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, POTASSIUM ION, ... | Authors: | Oberthuer, D, Achenbach, J, Gabdulkhakov, A, Falke, S, Buchner, K, Maasch, C, Rehders, D, Klussmann, S, Betzel, C. | Deposit date: | 2014-09-02 | Release date: | 2015-04-29 | Last modified: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2. Nat Commun, 6, 2015
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