PDB: 9935 resultsInfo pagesStatus searchChemie searchBIRD

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7YOW	Crystal structure of SARS-CoV-2 omicron variant spike receptor-binding domain (RBD) in complex with NCV2SG48 Fab Descriptor: Fab Heavy chain, Fab Light chain, SULFATE ION, ... Authors: Yamamoto, A, Higashiura, A. Deposit date: 2022-08-02 Release date: 2023-04-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants. Commun Biol, 6, 2023
8I5I	Crystal structure of SARS-CoV-2 delta variant spike receptor-binding domain (RBD) in complex with NCV2SG53 Fab Descriptor: Fab Heavy chain, Fab Light chain, Spike protein S1 Authors: Yamamoto, A, Higashiura, A. Deposit date: 2023-01-25 Release date: 2023-04-19 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants. Commun Biol, 6, 2023
8I5H	Crystal structure of SARS-CoV-2 delta variant spike receptor-binding domain (RBD) in complex with NCV2SG48 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab Light chain, ... Authors: Yamamoto, A, Higashiura, A. Deposit date: 2023-01-25 Release date: 2023-04-19 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants. Commun Biol, 6, 2023
5DJA	Fc Heterodimer Design 9.1 Y407M + T366I Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DI8	Fc Knob-Hole Heterodimer T366W + T366S/L368A/Y407V Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B. Deposit date: 2015-08-31 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJ0	Fc Heterodimer Design 11.2 Y349S/K370Y + E357D/S364Q Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJ2	Fc Heterodimer Design 7.4 Y407A + T366V/K409V Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJD	Fc Heterodimer Design 5.1 T366V + Y407F Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-02 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJ6	Fc Heterodimer Design 6.1 F405W/Y407A + T366M Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJ8	Fc Heterodimer Design 7.7 D399M/Y407A + T366V/K409I Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
5DJC	Fc Heterodimer Design 8.1 L368V/Y407A + T366V/K409F Descriptor: Fc-III peptide, IODIDE ION, Ig gamma-1 chain C region, ... Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
3J8V	Cryo-EM reconstruction of quasi-HPV16 complex with H16.14J Fab Descriptor: H16.14J heavy chain, H16.14J light chain, L1 Authors: Guan, J, Hafenstein, S. Deposit date: 2014-11-19 Release date: 2015-05-06 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (13.9 Å) Cite: Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization. Virology, 483, 2015
8GTO	cryo-EM structure of Omicron BA.5 S protein in complex with XGv282 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Xia, X.Y, Zhang, Y.Y, Chi, X.M, Huang, B.D, Wu, L.S, Zhou, Q. Deposit date: 2022-09-08 Release date: 2023-07-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants. Cell Discov, 9, 2023
7RP3	Crystal structure of GNE-1952 alkylated KRAS G12C in complex with 2H11 CLAMP Descriptor: 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, ... Authors: Oh, A, Tam, C, Wang, W. Deposit date: 2021-08-03 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
7RP2	Crystal structure of Kas G12C in complex with 2H11 CLAMP Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, GTPase KRas, ... Authors: Oh, A, Tam, C, Wang, W. Deposit date: 2021-08-03 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
3J8Z	Cryo-EM reconstruction of quasi-HPV16 complex with H16.1A Fab Descriptor: H16.1A heavy chain, H16.1A light chain, L1 Authors: Guan, J, Hafenstein, S. Deposit date: 2014-11-20 Release date: 2015-05-06 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (14 Å) Cite: Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization. Virology, 483, 2015
3J8W	Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab Descriptor: H263.A2 heavy chain, H263.A2 light chain, L1 Authors: Guan, J, Hafenstein, S. Deposit date: 2014-11-19 Release date: 2015-05-06 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (13 Å) Cite: Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization. Virology, 483, 2015
4JZN	Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1 Descriptor: Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, Envelope glycoprotein E2, ... Authors: Krey, T, Rey, F.A. Deposit date: 2013-04-03 Release date: 2013-06-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape. Plos Pathog., 9, 2013
4JZO	Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27 Descriptor: Anti-HCV E2 Fab HC84-27 heavy chain, Anti-HCV E2 Fab HC84-27 light chain, Envelope glycoprotein E2 Authors: Krey, T, Rey, F.A. Deposit date: 2013-04-03 Release date: 2013-06-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape. Plos Pathog., 9, 2013
8GTP	cryo-EM structure of Omicron BA.5 S protein in complex with XGv289 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Xia, X.Y, Zhang, Y.Y, Chi, X.M, Huang, B.D, Wu, L.S, Zhou, Q. Deposit date: 2022-09-08 Release date: 2023-07-12 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants. Cell Discov, 9, 2023
8GTQ	cryo-EM structure of Omicron BA.5 S protein in complex with S2L20 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Xia, X.Y, Zhang, Y.Y, Chi, X.M, Huang, B.D, Wu, L.S, Zhou, Q. Deposit date: 2022-09-08 Release date: 2023-07-12 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants. Cell Discov, 9, 2023
7FBJ	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing nanobody 17F6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, ... Authors: Zhu, J, Xu, T, Feng, B, Liu, J. Deposit date: 2021-07-11 Release date: 2022-07-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.85 Å) Cite: A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape. Small Methods, 6, 2022
7FBK	Crystal structure of SARS-CoV-2 receptor binding domain N501Y mutant in complex with neutralizing nanobody 20G6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, Spike protein S1 Authors: Zhu, J, Xu, T, Feng, B, Liu, J. Deposit date: 2021-07-11 Release date: 2022-07-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape. Small Methods, 6, 2022
5W1M	MACV GP1 CR1-07 Fab complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... Authors: Raymond, D.D, Clark, L.E, Abraham, J. Deposit date: 2017-06-03 Release date: 2018-05-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.91 Å) Cite: Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
5W1G	CR1-07 unliganded Fab Descriptor: CR1-07 Fab heavy chain, CR1-07 Fab light chain Authors: Raymond, D.D, Clark, L.E, Abraham, J. Deposit date: 2017-06-03 Release date: 2018-05-30 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018

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